5-BROMO-8-METHOXY-2-METHYL-QUINOLINE

5-BROMO-8-METHOXY-2-METHYL-QUINOLINE - Names and Identifiers

Name	5-Bromo-8-methoxy-2-methylquinoline
Synonyms	ZINC02534104 5-Bromo-8-methoxy-2-methylquinoline 5-Bromo-6-Methoxy-2-methylquinoline 5-bromo-8-methoxy-2-methyl-quinoline 5-BROMO-8-METHOXY-2-METHYL-QUINOLINE Quinoline, 5-bromo-8-methoxy-2-methyl-
CAS	103862-55-1
InChI	InChI=1S/C11H10BrNO/c1-7-3-4-8-9(12)5-6-10(14-2)11(8)13-7/h3-6H,1-2H3

5-BROMO-8-METHOXY-2-METHYL-QUINOLINE - Physico-chemical Properties

Molecular Formula	C11H10BrNO
Molar Mass	252.11
Density	1.455
Melting Point	114℃
Boling Point	341℃
Flash Point	160℃
pKa	3.01±0.50(Predicted)
Storage Condition	Sealed in dry,Room Temperature

5-BROMO-8-METHOXY-2-METHYL-QUINOLINE - Introduction

5-Bromo-8-methoxy-2-methylquinoline is an organic compound. Its molecular formula is C12H12BrNO, and the structural formula is as follows:

Br
|
OCH3
|
CH3

C
//
HN C
\
CH3

The following is a description of the properties, uses, preparation methods and safety information of the compound:

Nature:
1. Appearance: White crystalline solid.
2. Melting point: about 60-62°C.
3. Boiling point: about 211-212°C.
4. Solubility: limited solubility in water, soluble in organic solvents such as ethanol and dichloromethane.

Use:
1. 5-Bromo-8-methoxy-2-methylquinoline is often used as a pharmaceutical intermediate for the synthesis and research of other compounds.
2. It can be used to synthesize biologically active molecules, such as anti-tumor drugs.

Preparation Method:
There are many preparation methods of 5-bromo-8-methoxy-2-methylquinoline, one of which is a common method of synthesis through the following steps:
1. Methoxyacetic anhydride reacts with 2-methyl quinoline to generate 2-amino -8-methoxyquinoline.
2. reacting 2-amino -8-methoxyquinoline with bromoacetic acid to generate 5-bromo -8-methoxy -2-methyl quinoline.

Safety Information:
1. 5-Bromo-8-methoxy-2-methylquinoline is an organic compound, which should be used in accordance with laboratory safety procedures.
2. The compound may be irritating to the eyes, skin and respiratory tract, and direct contact should be avoided.
3. during use or storage, it should be kept in a cool, dry, well-ventilated place, and avoid contact with flammable substances.
4. Waste should be disposed of according to local regulations and should not be inverted at will.

Last Update：2024-04-09 02:00:40