5-BROMOQUINOLINE-8-CARBALDEHYDE

5-BROMOQUINOLINE-8-CARBALDEHYDE - Names and Identifiers

Name	5-BROMOQUINOLINE-8-CARBALDEHYDE
Synonyms	ine-8-carbaL 5-BROMOQUINOLINE-8-CARBALDEHYDE 8-Quinolinecarboxaldehyde, 5-broMo- 5-Bromo-8-formylquinoline, 5-Bromo-8-formyl-1-azanaphthalene
CAS	885267-41-4

5-BROMOQUINOLINE-8-CARBALDEHYDE - Physico-chemical Properties

Molecular Formula	C10H6BrNO
Molar Mass	236.06
Density	1.632±0.06 g/cm3(Predicted)
Boling Point	374.6±27.0 °C(Predicted)
pKa	2.37±0.29(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

5-BROMOQUINOLINE-8-CARBALDEHYDE - Risk and Safety

Hazard Symbols

Xi - Irritant

5-BROMOQUINOLINE-8-CARBALDEHYDE - Reference Information

preparation method

a preparation method of 5-bromoquinoline-8-formaldehyde, comprising the following steps: S1, mixing 5-bromo-2-methylaniline with glycerol, adding 75% concentrated sulfuric acid and catalytic amount of sodium iodide to co-heat to obtain 5-bromo-8-methylquinoline; S2, 5-bromo-8-methylquinoline is produced in the presence of NBS and AIBN to 5-bromo-8-dibromomethylquinoline, and the reaction solvent is DCE;S3, and then 5-bromo-8-dibromomethylquinoline is co-heated with a catalytic amount of sodium iodide in a mixed solvent of acetonitrile and water to obtain 5-bromoquinoline-8-formaldehyde.

Last Update：2024-04-09 21:01:54