5-Bromo-2,4-dimethoxy-1,3-diazine

5-Bromo-2,4-dimethoxy-1,3-diazine - Names and Identifiers

Name	5-bromo-2,4-dimethoxypyrimidine
Synonyms	Nsc81442 Bromo-2,4-dimethoxypyrimidine 5-BROMO-2,4-DIMETHOXPYRIMIDINE 2,4-DiMethoxy-5-broMopyriMidine 5-BROMO-2,6-DIMETHOXYPYRIMIDINE 5-bromo-2,4-dimethoxypyrimidine 5-Bromo-2,4-dimethoxy-1,3-diazine 5-BroMo-2,4-bis(Methyloxy)pyriMidine
CAS	56686-16-9
InChI	InChI=1/C6H7BrN2O2/c1-10-5-4(7)3-8-6(9-5)11-2/h3H,1-2H3

5-Bromo-2,4-dimethoxy-1,3-diazine - Physico-chemical Properties

Molecular Formula	C6H7BrN2O2
Molar Mass	219.04
Density	1.563±0.06 g/cm3(Predicted)
Melting Point	62-65 °C (lit.)
Boling Point	125 °C / 17mmHg
Flash Point	133.4°C
Solubility	Acetone, Dichloromethane
Vapor Presure	0.00245mmHg at 25°C
Appearance	Powder or Crystalline Powder
Color	White to pale yellow
pKa	1.27±0.29(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.533
MDL	MFCD00038016

5-Bromo-2,4-dimethoxy-1,3-diazine - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29335990

5-Bromo-2,4-dimethoxy-1,3-diazine - Introduction

5-bromo-2,4-dimethoxypyrimidine is an organic compound with the chemical formula C7H8BrN2O2.

Nature:
5-bromo-2,4-dimethoxypyrimidine is a white crystalline solid with a distinctive odor. It has a density of 1.46 g/mL and a melting point of 106-108°C. It is stable at room temperature, but will decompose when encountering high temperature and bright light.

Use:
5-bromo-2,4-dimethoxypyrimidine is often used as an intermediate in organic synthesis, especially in the preparation of fluorescent dyes and pesticides. It is also used to study pharmacology and medicinal chemistry.

Preparation Method:
The preparation of 5-bromo-2,4-dimethoxypyrimidine can be carried out by various methods. One common method is to react 2,4-dimethoxypyrimidine with hydrogen bromide. The reaction is usually carried out in an inert solvent, such as dimethylformamide or dimethylphosphoramidite, with heating at an appropriate temperature.

Safety Information:
5-bromo-2,4-dimethoxypyrimidine is irritating and corrosive, and may cause burns on contact with skin and eyes. Therefore, wear gloves and goggles when handling, and avoid breathing its dust or vapor. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. In addition, contact with oxidizing agents and strong acids should be avoided during storage to prevent accidental reactions.

Last Update：2024-04-09 20:52:54