5-Bromo-2-(dimethylamino)pyridine

5-Bromo-2-(dimethylamino)pyridine - Names and Identifiers

Name	5-bromo-2-(N,N-dimethyl-1-yl)pyridine
Synonyms	3-Bromo-6-dimethylaminopyridine 5-Bromo-2-(dimethylamino)pyridine 5-Bromo-N,N-dimethyl-2-pyridinamine 5-Bromo-N,N-dimethylpyridin-2-amine (5-bromo-pyridin-2-yl)-dimethylamine 2-Pyridinamine, 5-bromo-N,N-dimethyl- 5-bromo-2-(N,N-dimethyl-1-yl)pyridine 2-PyridinaMine, 5-broMo-N,N-diMethyl-
CAS	26163-07-5
InChI	InChI=1/C7H9BrN2/c1-10(2)7-4-3-6(8)5-9-7/h3-5H,1-2H3

5-Bromo-2-(dimethylamino)pyridine - Physico-chemical Properties

Molecular Formula	C7H9BrN2
Molar Mass	201.06
Density	1.469±0.06 g/cm3(Predicted)
Melting Point	69-71 °C
Boling Point	253.5±20.0 °C(Predicted)
Flash Point	107.1°C
Vapor Presure	0.0182mmHg at 25°C
pKa	5.31±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.592

5-Bromo-2-(dimethylamino)pyridine - Risk and Safety

Risk Codes	22 - Harmful if swallowed
Hazard Note	Irritant

5-Bromo-2-(dimethylamino)pyridine - Introduction

5-bromo-2-(N,N-dimethyl-1-yl)pyridine is an organic compound with the chemical formula C9H11BrN. Here are some of the properties and uses of the compound:

Nature:
1. Appearance: colorless liquid or solid.
2. Solubility: Soluble in organic solvents such as chloroform, acetone and dimethyl sulfoxide.
3. Melting Point: about 38-40 ° C
4. Boiling Point: about 285-287 C
5. Density: About 1.34g/cm3

Use:
1. 5-bromo-2-(N,N-dimethyl-1-yl)pyridine is widely used as an intermediate in organic synthesis, especially in the pharmaceutical field.
2. It can be used to synthesize other compounds containing pyridine ring structure, such as drugs, pesticides and additives.

Method:
5-bromo-2-(N,N-dimethyl-1-yl)pyridine can be prepared by the following steps:
1. Pyridine and bromine are reacted under appropriate reaction conditions to generate bromopyridine.
2. The bromopyridine is reacted with N,N-dimethylformamide under appropriate conditions to generate the target product.

Safety Information:
1. 5-bromo-2-(N,N-dimethyl-1-yl)pyridine should be regarded as a toxic compound and should be used under suitable operating conditions and follow relevant safety regulations.
2. During operation and storage, contact with skin, eyes and other mucous membranes should be avoided. If you come into contact with this compound, immediately flush the affected area with plenty of clean water and seek medical attention.
3. Use appropriate protective equipment such as gloves, goggles, and lab coats when handling the compound.
4. Waste shall be disposed in accordance with local regulations to minimize environmental pollution.

Last Update：2024-04-09 02:00:44