5-Bromo-2-hydroxy-4-methylpyridine
5-Bromo-2-hydroxy-4-picoline
CAS: 164513-38-6
Molecular Formula: C6H6BrNO
5-Bromo-2-hydroxy-4-methylpyridine - Names and Identifiers
5-Bromo-2-hydroxy-4-methylpyridine - Physico-chemical Properties
| Molecular Formula | C6H6BrNO |
| Molar Mass | 188.02 |
| Density | 1.5296 (rough estimate) |
| Melting Point | 198-202 °C (lit.) |
| Boling Point | 291.8±40.0 °C(Predicted) |
| Flash Point | 130.3°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.0019mmHg at 25°C |
| Appearance | Solid |
| Color | Off-white |
| pKa | 9.99±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.5500 (estimate) |
5-Bromo-2-hydroxy-4-methylpyridine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| Hazard Note | Harmful |
| Hazard Class | IRRITANT |
5-Bromo-2-hydroxy-4-methylpyridine - Introduction
It is an organic compound with the chemical formula C8H8BrNO. It has the following properties:
1. Appearance: It is a colorless or light yellow solid.
2. Solubility: It can be partially dissolved in water and is easily soluble in organic solvents such as ethanol and dimethyl sulfoxide.
3. PH value: It is neutral or slightly acidic in aqueous solution.
4. Reactivity: It is an electrophilic reagent that can participate in many organic reactions, such as electrophilic substitution reactions, oxidation reactions, etc.
5. Stability: It is stable at room temperature, but it may decompose under the action of high temperature, oxidant or strong acid.
It has a wide range of applications in the laboratory and industry, including the following:
1. As a chemical reagent: it can be used as an electrophilic reagent, Catalyst or reducing agent in organic synthesis.
2. As a preservative: Due to its antibacterial properties, it can be used for the preparation of preservatives, often used to protect wood, textiles, etc.
3. Medicine field: can be used in the synthesis of drugs or as intermediates for certain drugs.
A common method of preparing a salt is by reacting 2-picoline with bromine. Specific steps may refer to the following method: First, under appropriate reaction conditions, 2-methylpyridine is reacted with bromine to obtain 5-bromo-2-methylpyridine. Then, under alkaline conditions, 5-bromo -2-methyl pyridine is treated with sodium hydroxide to obtain.
Regarding safety information, the following should be noted when using or handling the metal:
1. Avoid direct contact with skin, eyes, respiratory system, etc. Wear appropriate personal protective equipment such as gloves, glasses and masks.
2. Keep a well-ventilated environment during use and avoid inhaling its vapor.
3. Storage should be placed in a sealed container, avoid direct sunlight and high temperature.
4. If accidentally swallowed or skin contact occurs, rinse immediately with plenty of water and seek medical help in time.
5. In the use or disposal of the compound, should comply with the local laws and regulations and safety procedures.
1. Appearance: It is a colorless or light yellow solid.
2. Solubility: It can be partially dissolved in water and is easily soluble in organic solvents such as ethanol and dimethyl sulfoxide.
3. PH value: It is neutral or slightly acidic in aqueous solution.
4. Reactivity: It is an electrophilic reagent that can participate in many organic reactions, such as electrophilic substitution reactions, oxidation reactions, etc.
5. Stability: It is stable at room temperature, but it may decompose under the action of high temperature, oxidant or strong acid.
It has a wide range of applications in the laboratory and industry, including the following:
1. As a chemical reagent: it can be used as an electrophilic reagent, Catalyst or reducing agent in organic synthesis.
2. As a preservative: Due to its antibacterial properties, it can be used for the preparation of preservatives, often used to protect wood, textiles, etc.
3. Medicine field: can be used in the synthesis of drugs or as intermediates for certain drugs.
A common method of preparing a salt is by reacting 2-picoline with bromine. Specific steps may refer to the following method: First, under appropriate reaction conditions, 2-methylpyridine is reacted with bromine to obtain 5-bromo-2-methylpyridine. Then, under alkaline conditions, 5-bromo -2-methyl pyridine is treated with sodium hydroxide to obtain.
Regarding safety information, the following should be noted when using or handling the metal:
1. Avoid direct contact with skin, eyes, respiratory system, etc. Wear appropriate personal protective equipment such as gloves, glasses and masks.
2. Keep a well-ventilated environment during use and avoid inhaling its vapor.
3. Storage should be placed in a sealed container, avoid direct sunlight and high temperature.
4. If accidentally swallowed or skin contact occurs, rinse immediately with plenty of water and seek medical help in time.
5. In the use or disposal of the compound, should comply with the local laws and regulations and safety procedures.
Last Update：2024-04-09 21:04:16
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View History
5-Bromo-2-hydroxy-4-methylpyridine
伊伐布雷定杂质29
2376278-70-3
Ethanol,2-[(2-Nitrophenyl)Amino]-
N-TERT-BUTYL-BENZOTHIAZOLE SULFENIMIDE
三异丙基硅烷
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2-(3-BROMO-PHENYLAMINO)-BENZOIC ACID
伊伐布雷定杂质29
2376278-70-3
Ethanol,2-[(2-Nitrophenyl)Amino]-
N-TERT-BUTYL-BENZOTHIAZOLE SULFENIMIDE
三异丙基硅烷
CNC
2-(3-BROMO-PHENYLAMINO)-BENZOIC ACID