5-Chloro-1H-indole-3-methanamine

5-Chloro-1H-indole-3-methanamine - Names and Identifiers

Name	5-Chloro-1H-Indol-3-Methylamine
Synonyms	(5-Chloro-1H-indol-3-yl) 5-Chloro-1H-Indol-3-Methylamine 5-CHLORO-1H-INDOL-3-METHYLAMINE 5-Chloro-1H-indole-3-methanamine 1H-Indole-3-methanamine, 5-chloro- (5-Chloro-1H-indol-3-yl)MethanaMine
CAS	113188-83-3

5-Chloro-1H-indole-3-methanamine - Physico-chemical Properties

Molecular Formula	C9H9ClN2
Molar Mass	180.63
Density	1.349
Boling Point	369.8±27.0 °C(Predicted)
pKa	16.22±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

5-Chloro-1H-indole-3-methanamine - Introduction

3-Aminomethyl-5-chloroindole is an organic compound with the chemical formula C9H8ClN. It is a compound with aromatic properties in the form of white crystals or powder.

One of the main uses of 3-aminomethyl-5-chloroindole is as a pharmaceutical intermediate. It can be used to synthesize anticancer drugs, antipsychotic drugs and antidepressant drugs, etc. In addition, it can also be used in the production of dyes, rubber additives and high-energy substances.

There are various methods for preparing 3-amine methyl -5-chloroindole. One common method is by reacting 3-chloroindole with methylamine. The specific operation is that 3-chloroindole is reacted with methylamine in an appropriate solvent by heating, crystallization, filtration and washing to obtain the target product.

When using and operating 3-aminomethyl-5-chloroindole, you need to pay attention to some safety information. It is an organic compound that may be irritating to the skin, eyes and respiratory tract. Therefore, appropriate personal protective equipment such as laboratory gloves, safety glasses and masks should be worn when handling it. At the same time, it is necessary to operate in a well-ventilated environment to avoid inhaling its vapors. If accidental contact with the skin or eyes, should immediately rinse with plenty of water, and timely medical treatment. When storing, it should be placed in a cool, dry, ventilated place, away from fire and combustible materials.

Last Update：2024-04-09 21:11:58