5-Chloro-2-cyanopyridine - Names and Identifiers
5-Chloro-2-cyanopyridine - Physico-chemical Properties
Molecular Formula | C6H3ClN2
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Molar Mass | 138.55 |
Density | 1.33±0.1 g/cm3(Predicted) |
Melting Point | 106-108℃ |
Boling Point | 110°C/3mmHg(lit.) |
Flash Point | 98.5°C |
Solubility | Methanol |
Vapor Presure | 0.0403mmHg at 25°C |
Appearance | Bright yellow crystal |
Color | Yellow Cyrstalline |
pKa | -2.60±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.565 |
MDL | MFCD03788835 |
5-Chloro-2-cyanopyridine - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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UN IDs | UN 3439 6.1/PG III |
HS Code | 29333990 |
Hazard Note | Toxic |
Hazard Class | 6.1 |
Packing Group | III |
5-Chloro-2-cyanopyridine - Introduction
5-Chloro-2-cyanopyridine is an organic compound with the chemical formula C6H3ClN2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 5-Chloro-2-cyanopyridine is a colorless to pale yellow crystalline solid.
-Melting point: Its melting point is 85-87°C.
-Solubility: Good solubility in common organic solvents.
Use:
- 5-Chloro-2-cyanopyridine is often used as an intermediate compound in organic synthesis.
-It is an important raw material for the synthesis of compounds such as drugs, pesticides and dyes.
-It can also be used as a substrate for organic synthesis catalysts.
Preparation Method:
- 5-Chloro-2-cyanopyridine can be obtained by chlorinating 2-cyanopyridine.
-The reaction is usually carried out under alkaline conditions to improve the reaction efficiency.
-Generally, a reagent such as stannous chloride or antimony chloride is used as a chlorinating agent in the reaction.
Safety Information:
- 5-Chloro-2-cyanopyridine is irritating and should be rinsed with water immediately when in contact with skin or eyes.
-When operating, wear appropriate protective gloves and goggles to ensure safety.
-The compound should be kept away from fire and high temperature to prevent fire and explosion.
-It should be stored in a sealed container and away from oxidants and strong acids.
Please note that this is only a general introduction, specific use should also refer to the relevant chemical literature and safety data sheets.
Last Update:2024-04-09 15:18:00