5-Chloro-2-hydroxynicotinonitrile - Risk and Safety
Hazard Class
IRRITANT
5-Chloro-2-hydroxynicotinonitrile - Introduction
It is an organic compound with the chemical formula C6H3ClN2O. It has the appearance of white crystals or crystalline powder. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Molecular weight: 150.56g/mol
-Melting point: 152-154°C
-Boiling point: 332.7°C
-Solubility: Insoluble in water, soluble in some organic solvents such as chloroform and methanol.
Use:
is an important intermediate compound, mainly used in organic synthesis. It can be used in the synthesis of various compounds containing 5-chloro-2-hydroxypyridinone groups, such as drugs, pesticides and functional materials.
Preparation Method:
The preparation method of calcium is generally accomplished by performing chlorination and hydroxylation reactions. The specific method can be the hydroxylation reaction of 2-cyano-5-chloropyridine, and the commonly used reactants are potassium hydroxide (KOH) or hydrogen chloride (HCl).
Safety Information:
-It is an organic compound and should be handled with care to avoid direct contact with skin and eyes.
-Personal protective equipment such as protective gloves, goggles and laboratory clothing should be worn during operation.
-It should be operated under well-ventilated laboratory conditions to avoid inhaling its aerosols.
-Keep away from ignition and oxidizing agents during storage and handling.
-In case of accidental contact or ingestion, seek medical attention immediately.