5-Chloro-6-methoxy-pyridine-3-carbaldehyde

5-Chloro-6-methoxy-pyridine-3-carbaldehyde - Names and Identifiers

Name	3-CHLORO-5-FORMYL-2-METHOXYPYRIDINE
Synonyms	5-Chloro-6-methoxynicotinaldehyde 3-CHLORO-5-FORMYL-2-METHOXYPYRIDINE 5-Chloro-6-methoxy-pyridine-3-carbaldehyde 5-Chloro-6-methoxypyridine-3-carboxaldehyde 3-Pyridinecarboxaldehyde, 5-chloro-6-Methoxy-
CAS	132865-44-2
InChI	InChI=1/C7H6ClNO2/c1-11-7-6(8)2-5(4-10)3-9-7/h2-4H,1H3

5-Chloro-6-methoxy-pyridine-3-carbaldehyde - Physico-chemical Properties

Molecular Formula	C7H6ClNO2
Molar Mass	171.58
Density	1.317
Melting Point	152℃
Boling Point	260.3±35.0 °C(Predicted)
pKa	-0.68±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.569

5-Chloro-6-methoxy-pyridine-3-carbaldehyde - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R43 - May cause sensitization by skin contact
Safety Description	36/37 - Wear suitable protective clothing and gloves.

5-Chloro-6-methoxy-pyridine-3-carbaldehyde - Introduction

2-Methoxy-3-chloro-5-aldehyde pyridine is an organic compound with the chemical formula C10H8ClNO2. Its molecular structure has a methoxy group (-OCH3) and a chlorine atom (-Cl) replacing two hydrogen atoms on the pyridine ring, and an aldehyde group (-CHO) replacing one hydrogen atom on the pyridine ring.

2-methoxy -3-chloro -5-aldehyde pyridine has a strong disinfection and antibacterial effect, commonly used in the pharmaceutical industry as a raw material for anti-infective drugs. In addition, it can also be used as an intermediate in organic synthesis and participate in the synthesis of various organic compounds. For example, it can be used in the preparation of pesticides, dyes and other compounds such as pharmaceuticals.

The method for preparing 2-methoxy-3-chloro-5-aldehyde pyridine is usually by reacting 2-methoxypyridine with chloroyl chloride to obtain 2-methoxy-3-chloropyridine, and then oxidizing 2-methoxy-3-chloropyridine to 2-methoxy-3-chloro-5-aldehyde pyridine by oxidation.

Safety issues need to be paid attention to when using and handling 2-methoxy-3-chloro-5-aldehyde pyridine. It is an organic solvent that is volatile and should be kept away from fire and high temperatures. Avoid inhaling its vapors and contact with skin and eyes during operation. Wear appropriate protective equipment such as gloves, goggles and face shields when using. It should be sealed during storage and placed in a cool, dry place, away from flammable materials and oxidants. In case of accidental contact or inhalation, seek medical attention.

Last Update：2024-04-09 20:52:54