5-Cyano-2-(trifluoromethyl)pyridine - Names and Identifiers
5-Cyano-2-(trifluoromethyl)pyridine - Physico-chemical Properties
Molecular Formula | C7H3F3N2
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Molar Mass | 172.11 |
Density | 1.37±0.1 g/cm3(Predicted) |
Melting Point | 37-41°C(lit.) |
Boling Point | 37-40°C 0,3mm |
Flash Point | 180°F |
BRN | 8199624 |
pKa | -2.89±0.22(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
5-Cyano-2-(trifluoromethyl)pyridine - Risk and Safety
Risk Codes | R28 - Very Toxic if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
R43 - May cause sensitization by skin contact
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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UN IDs | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Note | Irritant |
Hazard Class | 6.1 |
Packing Group | III |
5-Cyano-2-(trifluoromethyl)pyridine - Introduction
5-Cyano-2-(trifluoromethyl)pyridine is an organic compound with the chemical formula C7H2F3N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to yellow liquid or solid
-Melting point: 74-76 ° C
-Boiling point: 213-215 ° C
-Density: 1.38g/cm³
-Solubility: Soluble in ethanol, ether and chloroform, slightly soluble in water
Use:
- 5-Cyano-2-(trifluoromethyl)pyridine is an important reagent in organic synthesis and is widely used in the synthesis of various drugs, ligands and organometallic compounds.
-It is often used in the preparation of catalysts, such as silver oxide, platinum, palladium, ruthenium and other catalysts.
-It can also be used in the fields of organic light emitting diodes (OLED), liquid crystal displays (LCD) and optoelectronics.
Method:
- 5-Cyano-2-(trifluoromethyl)pyridine has many preparation methods. A common method is to react 2-trifluoromethylpyridine with sodium cyanide to generate the target product under alkaline conditions.
In addition, 2-trifluoromethylpyridine can also be reacted with other cyanating reagents, such as hydrogen cyanide or trifluoromethylcyanate.
Safety Information:
- 5-Cyano-2-(trifluoromethyl)pyridine is a chemical. You need to pay attention to safe operation during use, avoid contact with skin and eyes, and avoid inhaling its vapor.
-Need to use in a well-ventilated place, avoid operating in a closed space.
-During storage, avoid contact with oxidants, strong acids and alkalis to avoid dangerous reactions.
-If swallowed or touched by mistake, consult a doctor immediately and provide a chemical label or safety data sheet.
Last Update:2024-04-09 19:05:47