5-Fluoro-2-(trifluoromethyl)aniline

5-Fluoro-2-(trifluoromethyl)aniline - Names and Identifiers

Name	5-Fluoro-2-(trifluoromethyl)aniline
Synonyms	ZR CF FXFFF 2-AMINO-4-FLUOROBENZOTRIFLUORIDE 5-Fluor-2-(trifluormethyl)anilin 2-Amino-4-Fluorobenzotrifluoride 5-Fluoro-2-(trifluoromethyl)aniline 5-FLUORO-2-(TRIFLUOROMETHYL)ANILINE 5-Fluoro-2-(trifluoromethyl)benzenamine Benzenamine, 5-fluoro-2-(trifluoromethyl)- 5-Fluoro-2-(trifluoromethyl)aniline[2-Amino-4-fluorobenzotrifluoride] 2-AMino-4-fluorobenzotrifluoride[5-Fluoro-2-(trifluoroMethyl)aniline]
CAS	827-20-3
InChI	InChI=1/C7H5F4N/c8-4-1-2-5(6(12)3-4)7(9,10)11/h1-3H,12H2

5-Fluoro-2-(trifluoromethyl)aniline - Physico-chemical Properties

Molecular Formula	C7H5F4N
Molar Mass	179.11
Density	1.383±0.06 g/cm3(Predicted)
Melting Point	29-32℃
Boling Point	185.6±35.0 °C(Predicted)
Flash Point	74.4°C
Water Solubility	Insoluble in water.
Vapor Presure	0.692mmHg at 25°C
pKa	0.45±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.46
MDL	MFCD06660353

5-Fluoro-2-(trifluoromethyl)aniline - Risk and Safety

Hazard Symbols	T - Toxic
Hazard Class	6.1

5-Fluoro-2-(trifluoromethyl)aniline - Introduction

5-Fluoro-2-(trifluoromethyl)aniline(5-Fluoro-2-(trifluoromethyl)aniline) is an organic compound. It has a molecular formula of C7H5F4N and a molecular weight of 181.11g/mol. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 5-Fluoro-2-(trifluoromethyl) The aniline is a colorless to pale yellow solid.
-Melting point: Its melting point range is 56-58 degrees Celsius.
-Solubility: It has good solubility in methanol, dimethylformamide and ethanol.

Use:
-Pharmaceutical synthesis: 5-Fluoro-2-(trifluoromethyl)aniline can be used in organic synthesis as an intermediate or starting material. It can be used in the preparation of pharmaceuticals, dyes and other organic compounds.
-Pesticide synthesis: The compound can also be used for the synthesis of pesticides.

Preparation Method:
5-Fluoro-2-(trifluoromethyl)aniline has many preparation methods, and the common methods are as follows:
-amination reaction: 4-Fluorobenzotrifluoride is reacted with ammonia gas to obtain 5-Fluoro-2-(trifluoromethyl)aniline.
-Fluorination reaction: 5-Fluoro-2-(trifluoromethyl)aniline is obtained by reacting p-aminotoluene with fluorine gas for fluorination.

Safety Information:
- 5-Fluoro-2-(trifluoromethyl)aniline irritant, avoid contact with skin and eyes.
-During use, use appropriate personal protective equipment, such as chemical goggles and gloves.
-Waste disposal to comply with local laws and regulations, can not be dumped.
-In storage and transportation, pay attention to avoid high temperature, fire and humid environment.
-Keep away from flammable and oxidizing agents during use and storage.

Last Update：2024-04-09 02:00:48