5-Fluoro-2-hydroxyaniline
2-Amino-4-fluorophenol
CAS: 399-97-3
Molecular Formula: C6H6FNO
5-Fluoro-2-hydroxyaniline - Names and Identifiers
| Name | 2-Amino-4-fluorophenol |
| Synonyms | Aminofluorophenol1 2-AMINO-4-FLUOROPHEN 2-Amino-4-fluorophenol 5-Fluoro-2-hydroxyaniline 2- aMino-4-difluoro phenol 5-Fluoro-2-hydroxy aniline 6007 2-AMINO-4-FLUORO PHENOL |
| CAS | 399-97-3 |
| EINECS | 625-852-6 |
| InChI | InChI=1/C7H6FI/c1-5-2-3-6(9)4-7(5)8/h2-4H,1H3 |
5-Fluoro-2-hydroxyaniline - Physico-chemical Properties
| Molecular Formula | C6H6FNO |
| Molar Mass | 127.12 |
| Density | 1.347±0.06 g/cm3(Predicted) |
| Melting Point | 130-135 °C |
| Boling Point | 252.9±25.0 °C(Predicted) |
| Flash Point | 79.4°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.416mmHg at 25°C |
| Appearance | powder to crystal |
| Color | Light yellow to Brown |
| pKa | 9.77±0.18(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.58 |
5-Fluoro-2-hydroxyaniline - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29222990 |
| Hazard Class | IRRITANT |
5-Fluoro-2-hydroxyaniline - Introduction
2-Amino-4-fluorophenol(2-Amino-4-fluorophenol) is an organic compound with the chemical formula C6H6FNO.
The following are some of the properties of 2-Amino-4-fluorophenol:
-Appearance: White crystalline solid
-Melting point: 125-128°C
-Boiling Point: 318-320°C
-Solubility: Slightly soluble in water, soluble in ethanol, ether and acid.
2-Amino-4-fluorophenol is mainly used as an intermediate in organic synthesis and pharmaceutical manufacturing. Some specific applications include:
-as a synthetic intermediate for dyes and chemicals
-for the synthesis of drugs and pharmaceutical compounds
-For the preparation of electrochemical materials and coatings
The methods for preparing 2-Amino-4-fluorophenol mainly include:
-Through para-fluorination reaction: The p-aminophenol is reacted with a fluorinating reagent to generate 2-Amino-4-fluorophenol.
Regarding the safety information of 2-Amino-4-fluorophenol, due to its toxicity, the following matters need to be noted:
-Avoid inhaling its dust or vapors, as well as contact with skin and eyes
-Wear appropriate protective equipment such as gloves, goggles and masks when in use
-Store away from fire and oxidizers
-Waste disposal shall comply with local codes and regulations.
The following are some of the properties of 2-Amino-4-fluorophenol:
-Appearance: White crystalline solid
-Melting point: 125-128°C
-Boiling Point: 318-320°C
-Solubility: Slightly soluble in water, soluble in ethanol, ether and acid.
2-Amino-4-fluorophenol is mainly used as an intermediate in organic synthesis and pharmaceutical manufacturing. Some specific applications include:
-as a synthetic intermediate for dyes and chemicals
-for the synthesis of drugs and pharmaceutical compounds
-For the preparation of electrochemical materials and coatings
The methods for preparing 2-Amino-4-fluorophenol mainly include:
-Through para-fluorination reaction: The p-aminophenol is reacted with a fluorinating reagent to generate 2-Amino-4-fluorophenol.
Regarding the safety information of 2-Amino-4-fluorophenol, due to its toxicity, the following matters need to be noted:
-Avoid inhaling its dust or vapors, as well as contact with skin and eyes
-Wear appropriate protective equipment such as gloves, goggles and masks when in use
-Store away from fire and oxidizers
-Waste disposal shall comply with local codes and regulations.
Last Update：2024-04-09 19:05:49
