5-Fluoro-3-Methylpyridine
3-Fluoro-5-picoline
CAS: 407-21-6
Molecular Formula: C6H6FN
5-Fluoro-3-Methylpyridine - Names and Identifiers
| Name | 3-Fluoro-5-picoline |
| Synonyms | 5-FLUORO-3-PICOLINE 3-Fluoro-5-picoline 3-FLUORO-5-PICOLINE 3-Fluoro-5-methylpyridine 3-FLUORO-5-METHYLPYRIDINE 5-Fluoro-3-Methylpyridine Pyridine, 3-fluoro-5-methyl- |
| CAS | 407-21-6 |
| EINECS | 206-980-8 |
| InChI | InChI=1/C6H6FN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3 |
5-Fluoro-3-Methylpyridine - Physico-chemical Properties
| Molecular Formula | C6H6FN |
| Molar Mass | 111.12 |
| Density | 1.077±0.06 g/cm3(Predicted) |
| Boling Point | 139 °C(Press: 700 Torr) |
| Flash Point | 38.7°C |
| Vapor Presure | 7.66mmHg at 25°C |
| pKa | 3.10±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.477 |
| MDL | MFCD03095273 |
5-Fluoro-3-Methylpyridine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
5-Fluoro-3-Methylpyridine - Introduction
3-Fluoro-5-picoline is an organic compound with the chemical formula C6H6FN. It is a colorless liquid with a strong pungent odor.
3-Fluoro-5-picoline is commonly used as a reagent and intermediate in organic synthesis. It has important applications in the pesticide, pharmaceutical and dye industries. It can be used to synthesize some specific drug molecules, such as antibiotics, anti-tumor drugs and pesticides.
3-Fluoro-5-picoline can be prepared by reacting pyridine with hydrogen fluoride. First, pyridine is reacted with hydrogen fluoride under appropriate conditions to obtain 3-fluoropyridine. 3-Fluoro-5-picoline can then be prepared by reacting 3-fluoropyridine with a methylating agent, such as methyl iodide or methyl bromide.
For safety information about 3-Fluoro-5-picoline, it may be irritating to the skin, eyes and respiratory tract. At the same time, it is also toxic and may be harmful to aquatic organisms. Therefore, it is necessary to follow the correct operation method during use and use appropriate personal protective equipment, such as protective gloves and goggles. At the same time, it needs to be stored in a sealed container, away from fire sources and flammable materials. In case of accidental poisoning or exposure to this compound, seek medical attention immediately.
3-Fluoro-5-picoline is commonly used as a reagent and intermediate in organic synthesis. It has important applications in the pesticide, pharmaceutical and dye industries. It can be used to synthesize some specific drug molecules, such as antibiotics, anti-tumor drugs and pesticides.
3-Fluoro-5-picoline can be prepared by reacting pyridine with hydrogen fluoride. First, pyridine is reacted with hydrogen fluoride under appropriate conditions to obtain 3-fluoropyridine. 3-Fluoro-5-picoline can then be prepared by reacting 3-fluoropyridine with a methylating agent, such as methyl iodide or methyl bromide.
For safety information about 3-Fluoro-5-picoline, it may be irritating to the skin, eyes and respiratory tract. At the same time, it is also toxic and may be harmful to aquatic organisms. Therefore, it is necessary to follow the correct operation method during use and use appropriate personal protective equipment, such as protective gloves and goggles. At the same time, it needs to be stored in a sealed container, away from fire sources and flammable materials. In case of accidental poisoning or exposure to this compound, seek medical attention immediately.
Last Update：2024-04-09 21:54:55
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