5-Fluoro-3-nitroaniline
3-fluoro-5-nitroaniline
CAS: 2369-12-2
Molecular Formula: C6H5FN2O2
5-Fluoro-3-nitroaniline - Names and Identifiers
| Name | 3-fluoro-5-nitroaniline |
| Synonyms | 5-Fluoro-3-nitroaniline 5-FLUORO-3-NITROANILINE 3-fluoro-5-nitroaniline 3-Fluoro-5-Nitro-Phenylamine benzenamine, 3-fluoro-5-nitro- Benzenamine, 3-fluoro-5-nitro- 3-Fluoro-5-nitro-1-benzenamine (3-fluoro-5-nitro-phenyl)amine |
| CAS | 2369-12-2 |
| EINECS | 219-129-0 |
| InChI | InChI=1/C6H5FN2O2/c7-4-1-5(8)3-6(2-4)9(10)11/h1-3H,8H2 |
5-Fluoro-3-nitroaniline - Physico-chemical Properties
| Molecular Formula | C6H5FN2O2 |
| Molar Mass | 156.11 |
| Density | 1.448±0.06 g/cm3(Predicted) |
| Melting Point | 115-116 °C |
| Boling Point | 314.3±22.0 °C(Predicted) |
| Flash Point | 143.9°C |
| Vapor Presure | 0.000469mmHg at 25°C |
| pKa | 1.24±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.603 |
5-Fluoro-3-nitroaniline - Introduction
3-fluoro-5-nitroaniline is an organic compound with the chemical formula C6H5FNO2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 3-fluoro-5-nitroaniline is a pale yellow crystal.
-Melting point: It has a relatively high melting point, about 159-161 degrees Celsius.
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide.
Use:
-Chemical synthesis: 3-fluoro-5-nitroaniline can be used in organic synthesis reactions as an important intermediate.
-Drug research: It can also be used in drug research as a starting point for drug synthesis and structural improvement.
Method:
- 3-fluoro-5-nitroaniline can be prepared by fluorination of p-nitroaniline. A specific preparation method may be by reacting a fluorinating agent (such as ammonium trichlorofluoroborate) with nitroaniline under appropriate conditions.
Safety Information:
- 3-fluoro-5-nitroaniline should be considered as a toxic and irritant substance. When using or handling this compound, follow appropriate laboratory practices and safety measures, including wearing appropriate personal protective equipment (such as gloves, goggles, and lab clothes).
-Avoid inhalation, contact with skin and eyes. Ventilation equipment should be used during operation to reduce the concentration of harmful gases.
Nature:
-Appearance: 3-fluoro-5-nitroaniline is a pale yellow crystal.
-Melting point: It has a relatively high melting point, about 159-161 degrees Celsius.
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide.
Use:
-Chemical synthesis: 3-fluoro-5-nitroaniline can be used in organic synthesis reactions as an important intermediate.
-Drug research: It can also be used in drug research as a starting point for drug synthesis and structural improvement.
Method:
- 3-fluoro-5-nitroaniline can be prepared by fluorination of p-nitroaniline. A specific preparation method may be by reacting a fluorinating agent (such as ammonium trichlorofluoroborate) with nitroaniline under appropriate conditions.
Safety Information:
- 3-fluoro-5-nitroaniline should be considered as a toxic and irritant substance. When using or handling this compound, follow appropriate laboratory practices and safety measures, including wearing appropriate personal protective equipment (such as gloves, goggles, and lab clothes).
-Avoid inhalation, contact with skin and eyes. Ventilation equipment should be used during operation to reduce the concentration of harmful gases.
Last Update：2024-04-09 02:00:44
