Molecular Formula | C4H3FN2O2 |
Molar Mass | 130.08 |
Density | 1.73±0.1 g/cm3(Predicted) |
Boling Point | 295.4°C at 760 mmHg |
Flash Point | 132.4°C |
Vapor Presure | 0.000869mmHg at 25°C |
pKa | 3.42±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.612 |
HS Code | 29335990 |
Hazard Class | IRRITANT |
Introduction | 5-fluoro-4, 6-dihydroxypyrimidine is the starting material for many drug synthesis, especially an important intermediate for many hydroxypyrimidine compounds. |
Preparation | Using 3-fluoropyrimidine as raw material, under the action of solvent acetone and 1.5 atmospheres, at a temperature of 120 ℃-160 ℃, respectively The synthesis method of hydroxylation and displacement reactions to generate 5-fluoro-4, 6-dihydroxypyrimidine. The purity of this crude product can meet the general reaction requirements and can be directly put into the reaction. |