5-HYDROXY-2-COUMARANONE

5-HYDROXY-2-COUMARANONE - Names and Identifiers

Name	2,5-Dihydroxyphenylacetic acid Gamma-lactone
Synonyms	AKOS BBS-00000246 Homogentisic lactone 5-HYDROXY-2-COUMARANONE 5-hydroxybenzofuran-2-one Homogentisic acidγ-lactone Homogentisic acid gamma-lactone 5-hydroxy-1-benzofuran-2(3H)-one 2,3-DIHYDRO-5-HYDROXYBENZOFURAN-2-ONE 2,5-DIHYDROXYPHENYLACETIC ACID LACTONE 2,5-DIHYDROXYPHENYLACETIC GAMMA-LACTONE 2,5-DIHYDROXYPHENYLACETIC ACID GAMMA-LACTONE 2,5-Dihydroxyphenylacetic acid Gamma-lactone 5-Hydroxybenzofuran-2(3H)-one, Homogentisic lactone
CAS	2688-48-4
EINECS	220-252-7
InChI	InChI=1/C8H6O3/c9-6-1-2-7-5(3-6)4-8(10)11-7/h1-3,9H,4H2

5-HYDROXY-2-COUMARANONE - Physico-chemical Properties

Molecular Formula	C8H6O3
Molar Mass	150.13
Density	1.436
Melting Point	192-194°C
Boling Point	231.65°C (rough estimate)
Flash Point	167.7°C
Solubility	Acetone, Ethyl Acetate, DMSO
Vapor Presure	2.08E-05mmHg at 25°C
Appearance	Solid
Color	Pale Brown
BRN	128621
pKa	9.28±0.20(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.4500 (estimate)
MDL	MFCD00005857

5-HYDROXY-2-COUMARANONE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	8-10-23
HS Code	29163990

5-HYDROXY-2-COUMARANONE - Introduction

2,5-dihydroxyethylacetic Gamma-lactone is an organic compound with the formula C8H6O4. It is colorless crystal or white crystalline powder, soluble in water and common organic solvents.

It has a natural aroma, so it is widely used in food, spices and flavors and other industries. It can also be used as an important intermediate and reagent in organic synthesis. In addition, 2,5-dihydroxyphenylacetic Gamma-lactone also has some pharmacological activities, including antibacterial, antioxidant and anti-inflammatory effects.

The method for preparing 2,5-dihydroxyphenylacetic acid Gamma-lactone is generally obtained by lactonization of 2,5-dihydroxyphenylacetic acid with a small amount of acid catalyst at an appropriate temperature. The specific preparation steps and conditions can be adjusted as needed.

Regarding safety information, the 2,5-dihydroxyphenylacetic acid Gamma-lactone has not reported specific toxicity or harmfulness at this time. However, as a chemical substance, care should be taken to follow correct safety procedures, avoid contact with skin and eyes, and avoid inhalation or ingestion. If accidental contact or misuse, should immediately seek medical attention.

Last Update：2024-04-09 20:52:54