5-HYDROXY-2-METHOXYPYRIDINE
2-Methoxy-5-hydroxypyridine
CAS: 51834-97-0
Molecular Formula: C6H7NO2
5-HYDROXY-2-METHOXYPYRIDINE - Names and Identifiers
5-HYDROXY-2-METHOXYPYRIDINE - Physico-chemical Properties
| Molecular Formula | C6H7NO2 |
| Molar Mass | 125.13 |
| Density | 1.190±0.06 g/cm3(Predicted) |
| Melting Point | 81 °C |
| Boling Point | 330.1±22.0 °C(Predicted) |
| Flash Point | 153.5°C |
| Vapor Presure | 8.83E-05mmHg at 25°C |
| pKa | 9.69±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.538 |
| Physical and Chemical Properties | ;
|
5-HYDROXY-2-METHOXYPYRIDINE - Risk and Safety
| Hazard Class | IRRITANT |
5-HYDROXY-2-METHOXYPYRIDINE - Introduction
2-Methoxy-5-hydroxypyridine is an organic compound with the chemical formula C6H7NO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Methoxy-5-hydroxypyridine is a white to yellow crystalline powder.
-Solubility: It can be dissolved in water, alcohols and acid solvents, insoluble in ketone and ether solvents.
-Melting point: Its melting point is about 125-129°C.
Use:
-Pharmaceutical field: 2-Methoxy-5-hydroxypyridine is commonly used in the synthesis of synthetic drugs, especially antiviral drugs and anti-tumor drugs.
-Chemical research: It can be used as an intermediate in organic synthesis reactions and has important application value in the synthesis of complex organic compounds.
Preparation Method:
2-Methoxy-5-hydroxypyridine can generally be prepared by the following methods:
1. pyridine and methanol react to generate 2-methoxypyridine.
2. 2-Methoxypyridine is reacted with sodium hydroxide or sodium bicarbonate to generate 2-Methoxy-5-hydroxypyridine.
Safety Information:
- 2-Methoxy-5-hydroxypyridine is generally considered to be a low-toxic compound.
-During use, avoid inhaling its dust or contact with skin and eyes.
-If accidental inhalation or skin contact occurs, rinse immediately with water and seek medical help.
-In storage and handling, should comply with the safety procedures, and away from the fire and high temperature environment.
Nature:
-Appearance: 2-Methoxy-5-hydroxypyridine is a white to yellow crystalline powder.
-Solubility: It can be dissolved in water, alcohols and acid solvents, insoluble in ketone and ether solvents.
-Melting point: Its melting point is about 125-129°C.
Use:
-Pharmaceutical field: 2-Methoxy-5-hydroxypyridine is commonly used in the synthesis of synthetic drugs, especially antiviral drugs and anti-tumor drugs.
-Chemical research: It can be used as an intermediate in organic synthesis reactions and has important application value in the synthesis of complex organic compounds.
Preparation Method:
2-Methoxy-5-hydroxypyridine can generally be prepared by the following methods:
1. pyridine and methanol react to generate 2-methoxypyridine.
2. 2-Methoxypyridine is reacted with sodium hydroxide or sodium bicarbonate to generate 2-Methoxy-5-hydroxypyridine.
Safety Information:
- 2-Methoxy-5-hydroxypyridine is generally considered to be a low-toxic compound.
-During use, avoid inhaling its dust or contact with skin and eyes.
-If accidental inhalation or skin contact occurs, rinse immediately with water and seek medical help.
-In storage and handling, should comply with the safety procedures, and away from the fire and high temperature environment.
Last Update：2024-04-09 15:17:58
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CAS: 51834-97-0
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