5-Hydroxypyridine-2-carbaldehyde

5-Hydroxypyridine-2-carbaldehyde - Names and Identifiers

Name	5-hydroxypyridine-2-carbaldehyde
Synonyms	NSC 127948 NSC 129151 6-Formyl-3-pyridinol 2-ForMyl-5-hydroxypyridine 5-Hydroxypyridine-2-carbaldehyde 5-hydroxypyridine-2-carbaldehyde 2-pyridinecarboxaldehyde, 5-hydroxy- 5-hydroxy-2-pyridine carboxylic aldehyde 5-Hydroxypicolinaldehyde, 2-Formyl-5-hydroxypyridine
CAS	31191-08-9
InChI	InChI=1/C6H5NO2/c8-4-5-1-2-6(9)3-7-5/h1-4,9H

5-Hydroxypyridine-2-carbaldehyde - Physico-chemical Properties

Molecular Formula	C6H5NO2
Molar Mass	123.11
Density	1.327±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	363.5±22.0 °C(Predicted)
Flash Point	173.7°C
Vapor Presure	8.56E-06mmHg at 25°C
pKa	3.17±0.18(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.629

5-Hydroxypyridine-2-carbaldehyde - Reference

Reference

1. Zhang, Jun, et al. "Inhibition of Maillard reaction in production of low-molecular-weight chitosan by enzymatic hydrolysis." Carbohydrate polymers 236 (2020): 116059.https://doi.org/10.1016/j.carbpol.2020.116059

5-Hydroxypyridine-2-carbaldehyde - Introduction

It is an organic compound with the chemical formula C6H5NO2. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Usually white or light yellow crystals.
-Solubility: It can be dissolved in water and most organic solvents, such as ethanol and chloroform.

Use:
-is often used as an important intermediate in organic synthesis. It can be used in the synthesis of compounds such as pyridine and acyl pyridine.
-It can also be used to synthesize reactive dyes and photosensitive compounds.
-It also has certain applications in the field of medicine, such as the precursor of synthetic drug molecules.

Method:
-br can be prepared by hydroxymethylation of 2-pyridinecarboxamide.
-This reaction can be achieved by reacting 2-pyridinecarboxamide with methanol in the presence of a base.

Safety Information:
-It is relatively stable under general conditions, but contact with strong oxidants and strong acids should be avoided.
-Avoid inhalation, ingestion and skin contact during operation. Wear appropriate personal protective equipment such as gloves and goggles when necessary.
-If inhalation or ingestion occurs, seek medical attention immediately.

Last Update：2024-04-09 02:00:45