5-METHOXY-2-CARBETHOXYINDOLE

5-METHOXY-2-CARBETHOXYINDOLE - Names and Identifiers

Name	5-methoxyindole-2-carboxylic acid ethyl ester
Synonyms	5-METHOXY-2-CARBETHOXYINDOLE ethyl5-methoxy-2-indolecarboxylate ETHYL 5-METHOXYINDOLE-2-CARBOXYLATE Ethyl 5-methoxyindole-2-carboxylate methoxy-5indolecarboxylated'ethyle-2 Ethyl 5-methoxy-1H-indole-2-carboxylate Methoxy-5 indole carboxylate d'ethyle-2 ETHYL 5-METHOXY-1H-INDOLE-2-CARBOXYLATE 5-methoxy-indole-2-carboxylicaciethylester 5-22-05-00181 (Beilstein Handbook Reference) 5-METHOXYINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 5-methoxyindole-2-carboxylic acid ethyl ester 5-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER 1H-Indole-2-carboxylic acid, 5-methoxy-, ethyl ester
CAS	4792-58-9
InChI	InChI=1/C12H13NO3/c1-3-16-12(14)11-7-8-6-9(15-2)4-5-10(8)13-11/h4-7,13H,3H2,1-2H3
InChIKey	NPIUAXNFAUGNHP-UHFFFAOYSA-N

5-METHOXY-2-CARBETHOXYINDOLE - Physico-chemical Properties

Molecular Formula	C12H13NO3
Molar Mass	219.24
Density	1.216±0.06 g/cm3(Predicted)
Melting Point	154-157°C
Boling Point	380.2±22.0 °C(Predicted)
Flash Point	183.7°C
Water Solubility	Insoluble in water.
Vapor Presure	5.54E-06mmHg at 25°C
Appearance	crystalline
Color	yellow to orange
BRN	178104
pKa	14.72±0.30(Predicted)
Storage Condition	-20°C
Refractive Index	1.599
MDL	MFCD00047163
Use	Reactant for preparation of: Ligands with binding specificity towards the GABA receptor Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes Anticancer agents Integrase strand-transfer inhibitor

5-METHOXY-2-CARBETHOXYINDOLE - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
RTECS	NL6010000
Hazard Class	IRRITANT

5-METHOXY-2-CARBETHOXYINDOLE - Introduction

Acid ethyl ester is an organic compound with the chemical formula C12H13NO3. It has the following properties:

1. Appearance: acid ethyl ester is a white solid or powdery substance.

2. solubility: it can be dissolved in common organic solvents (such as ether, methanol, dichloromethane, etc.).

3. Melting point: The melting point of the compound is 110-113°C.

4. chemical reaction: acid ethyl ester can undergo ester hydrolysis to generate 5-methoxy indole-2-formic acid.

acid ethyl ester has some uses:

1. Chemical synthesis: It is an intermediate in organic synthesis and can be used to prepare other oxygen-containing compounds.

2. Pharmaceutical research: The compound is used as a synthetic drug and drug precursor, especially in the research of anti-cancer and nervous system drugs.

A common method for preparing acid ethyl ester is to esterify 5-methoxyindole and ethyl acetate through a reaction.

Regarding safety information, the specific toxicity of acid ethyl ester has not been reported in detail. However, as users of chemicals, general chemical safety measures should be followed during handling and storage, such as wearing appropriate personal protective equipment, avoiding contact with skin and eyes, and ensuring that the operation is well ventilated. Before using this compound, it is best to understand the relevant safety data sheet and follow the operating instructions. If any accident or discomfort occurs, seek medical help immediately.

Last Update：2024-04-09 21:32:41