5-Nitroindolin-2-one - Names and Identifiers
5-Nitroindolin-2-one - Physico-chemical Properties
Molecular Formula | C8H6N2O3
|
Molar Mass | 178.14 |
Density | 1.449±0.06 g/cm3(Predicted) |
Melting Point | 233-236 °C |
Boling Point | 411.4±45.0 °C(Predicted) |
Flash Point | 202.593°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | Crystallization |
pKa | 12.61±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.632 |
MDL | MFCD00456999 |
5-Nitroindolin-2-one - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R43 - May cause sensitization by skin contact
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
|
WGK Germany | 3 |
Hazard Note | Irritant/Keep Cold |
5-Nitroindolin-2-one - Introduction
5-Nitrooxindole, chemical formula C8H5N3O3, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-Nitrooxindole as a yellow crystalline solid.
-Solubility: It has better solubility in organic solvents, but lower solubility in water.
-Melting point: 5-Nitrooxindole has a high melting point, about 200-210 degrees Celsius.
Use:
-Chemical reagent: 5-Nitrooxindole is commonly used as an intermediate and reagent for organic synthesis.
-Fluorescent dye: It has fluorescent activity and can be used as a dye in biomedical research, staining and microscopic labeling.
Method:
The preparation method of 5-Nitrooxindole is mainly through the following reaction pathways:
-It can be prepared by the reaction of indolone and nitric acid, and the reaction conditions are usually at room temperature.
-In addition, 5-Nitrooxindole can also be prepared by the reaction of indole and nitric acid.
Safety Information:
- 5-Nitrooxindole may be harmful to human body and environment, so it is necessary to follow relevant safety operation procedures when using and handling.
-Inhalation or exposure to 5-Nitrooxindole may cause respiratory irritation, eye and skin irritation, so wear appropriate protective gloves, glasses and a mask.
-During storage and disposal, it needs to be stored separately from other chemicals to avoid contact with combustibles or oxidants.
-In case of inadvertent inhalation or contact, immediately stay away from the source and seek medical help.
Last Update:2024-04-10 22:29:15