5-acetyl-2(1H)-Pyridinone
2(1H)-Pyridinone, 5-acetyl- (9CI)
CAS: 1124-29-4
Molecular Formula: C7H7NO2
5-acetyl-2(1H)-Pyridinone - Names and Identifiers
| Name | 2(1H)-Pyridinone, 5-acetyl- (9CI) |
| Synonyms | 5-Acetylpyridin-2(1H) 5-Acetylpyridin-2(1H)-one 5-acetyl-2(1H)-Pyridinone 5-acetyl-1H-pyridin-2-one 3-Acethyl-6-hydroxypyridine 2(1H)-Pyridinone, 5-acetyl- (9CI) 1-(6-Hydroxypyridin-3-yl)ethanone ethanone, 1-(6-hydroxy-3-pyridinyl)- 1-(6-hydroxypyridin-3-yl)ethan-1-one |
| CAS | 1124-29-4 |
| InChI | InChI=1/C7H7NO2/c1-5(9)6-2-3-7(10)8-4-6/h2-4H,1H3,(H,8,10) |
5-acetyl-2(1H)-Pyridinone - Physico-chemical Properties
| Molecular Formula | C7H7NO2 |
| Molar Mass | 137.14 |
| Density | 1.217g/cm3 |
| Boling Point | 364.7°C at 760 mmHg |
| Flash Point | 174.4°C |
| Vapor Presure | 7.87E-06mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.557 |
5-acetyl-2(1H)-Pyridinone - Introduction
2-Hydroxy-5-acetylpyridine (2-hydroxy-5-acetylpyridine) is an organic compound with the chemical formula C7H7NO2. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Hydroxy-5-acetylpyridine is a white to yellow crystal or a crystalline powdery solid.
-Melting point: about 88-90 degrees Celsius.
-Solubility: 2-hydroxy-5-acetylpyridine has poor solubility in water and is soluble in organic solvents such as alcohols and ketones.
Use:
-Chemical reagent: 2-hydroxy-5-acetylpyridine can be used as a reagent in organic synthesis, such as for the preparation of other compounds.
-Complex ligand: 2-hydroxy-5-acetylpyridine has coordination ability and can form complexes with metal ions for catalytic reactions or extraction of metal ions.
-Drug research: It is also used in drug research as an intermediate or auxiliary reagent for certain drugs.
Preparation Method:
2-Hydroxy-5-acetylpyridine can be synthesized by the following steps:
1. pyridine reacts with ethyl phthalide to generate 5-acetyl pyridine.
2.5-Acetylpyridine is reacted with sodium hydroxide (NaOH) to generate 2-hydroxy-5-acetylpyridine.
Safety Information:
-2-hydroxy-5-acetylpyridine is a general organic compound. When using it, you need to pay attention to basic laboratory safety practices, such as wearing appropriate personal protective equipment and avoiding contact with skin, eyes and respiratory tract.
-It should be operated in a well-ventilated place to avoid entering the human body.
-If taken by mistake or in contact with skin, rinse immediately with plenty of water and seek medical help.
Please note that detailed information on the use and handling of chemical substances should be referred to the safety data sheet (SDS) or consult a professional chemist.
Nature:
-Appearance: 2-Hydroxy-5-acetylpyridine is a white to yellow crystal or a crystalline powdery solid.
-Melting point: about 88-90 degrees Celsius.
-Solubility: 2-hydroxy-5-acetylpyridine has poor solubility in water and is soluble in organic solvents such as alcohols and ketones.
Use:
-Chemical reagent: 2-hydroxy-5-acetylpyridine can be used as a reagent in organic synthesis, such as for the preparation of other compounds.
-Complex ligand: 2-hydroxy-5-acetylpyridine has coordination ability and can form complexes with metal ions for catalytic reactions or extraction of metal ions.
-Drug research: It is also used in drug research as an intermediate or auxiliary reagent for certain drugs.
Preparation Method:
2-Hydroxy-5-acetylpyridine can be synthesized by the following steps:
1. pyridine reacts with ethyl phthalide to generate 5-acetyl pyridine.
2.5-Acetylpyridine is reacted with sodium hydroxide (NaOH) to generate 2-hydroxy-5-acetylpyridine.
Safety Information:
-2-hydroxy-5-acetylpyridine is a general organic compound. When using it, you need to pay attention to basic laboratory safety practices, such as wearing appropriate personal protective equipment and avoiding contact with skin, eyes and respiratory tract.
-It should be operated in a well-ventilated place to avoid entering the human body.
-If taken by mistake or in contact with skin, rinse immediately with plenty of water and seek medical help.
Please note that detailed information on the use and handling of chemical substances should be referred to the safety data sheet (SDS) or consult a professional chemist.
Last Update：2024-04-09 19:05:45
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