5-amino-1,3-dihydro-2H-indol-2-one

5-amino-1,3-dihydro-2H-indol-2-one - Names and Identifiers

Name	5-Aminooxindole
Synonyms	5-Aminooxindole CHEMBRDG-BB 4006397 TIMTEC-BB SBB010120 5-aminoindolin-2-one 5-amino-2-indolinone 5-Amino-1,3-dihydro-indol... 5-Amino-1,3-dihydro-indol-2-one 5-amino-1,3-dihydro-2H-indol-2-one 5-amino-3,3a-dihydro-1H-indol-2(7aH)-one 5-Amino-1,3-dihydro-2H-indol-2-one, 5-Aminoindolin-2-one
CAS	20876-36-2
InChI	InChI=1/C8H8N2O/c9-6-1-2-7-5(3-6)4-8(11)10-7/h1-3H,4,9H2,(H,10,11)

5-amino-1,3-dihydro-2H-indol-2-one - Physico-chemical Properties

Molecular Formula	C8H8N2O
Molar Mass	148.16
Density	1.307±0.06 g/cm3(Predicted)
Melting Point	182-186°C
Boling Point	416.8±45.0 °C(Predicted)
Flash Point	205.8°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	3.73E-07mmHg at 25°C
Appearance	Yellow to brown crystalline powder
Color	Dark Green to Brown
pKa	13.91±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.653
MDL	MFCD02179603

5-amino-1,3-dihydro-2H-indol-2-one - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class	IRRITANT

5-amino-1,3-dihydro-2H-indol-2-one - Introduction

5-Aminooxindole is an organic compound often abbreviated as 5-AI. The following is its nature, use, preparation and safety information:

Nature:
5-Aminooxindole is a white solid powder with a unique amino ketone structure. It is stable at normal temperature but readily dissolves in organic solvents such as ethanol and dimethyl sulfoxide.

Use:
5-Aminooxindole has a wide range of applications in the field of chemical synthesis. It can be used as an important intermediate in the synthesis of organic compounds for the synthesis of drugs, dyes, pesticides and other organic compounds. It can also be used as a raw material for chemical fluorescent indicators and coating materials.

Method:
There are a variety of synthetic methods for 5-Aminooxindole. A common method is synthesis by reacting indol-2-one with ammonia. The specific steps include reacting indole -2-one with ammonia under appropriate reaction conditions, and the reaction product is crystallized, filtered, and dried to obtain a pure product.

Safety Information:
Regarding the safety of 5-Aminooxindole, there are currently no reports indicating that it has particularly serious toxicity. However, as a chemical substance, caution is still required in contact and use. Wear gloves, goggles and laboratory clothing to avoid direct contact with skin and eyes. Before use should read the relevant safety information, and strictly follow the safety procedures. In the event of inadvertent contact or inhalation, wash the affected area immediately and seek medical help if necessary.

Last Update：2024-04-09 21:54:55