5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid

5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid - Names and Identifiers

Name	5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid
Synonyms	5-Amino-2-hydroxy-4 Mesalamine EP Impurity P 3-(4-Sulfophenyl)-5-aminosalicylic Acid RS* 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid 5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid 5-amino-2-hydroxy-4'-sulfo-[1,1'-biphenyl]-3-carboxylic acid
CAS	887256-40-8

5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid - Physico-chemical Properties

Molecular Formula	C13H11NO6S
Molar Mass	309.29
Melting Point	>272°C (dec.)
Appearance	Form Solid, color White to Light Brown
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere
Stability	Hygroscopic
Physical and Chemical Properties	The bioactive Mesalamine impurity P is a Mesalamine (HY-15027) impurity. 5-Aminosalicic acid (Mesalamine) is a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

5-amino-2-hydroxy-4-sulfobiphenyl-3-carboxylicacid - Reference

Reference

1. Cui Li, Ning Qing, Zhang Runtong, Liu Guo-guang, Zhong Rongling, Xia Zhi, Wang Jing. Optimization of extraction conditions of polysaccharide from Scutellaria baicalensis Georgi and its effect on ulcerative colitis in mice [J]. Shandong Journal of Traditional Chinese Medicine, 2020, v.39;No.395(09):101-108.