5-beta-hydroxy-19-oxodigitoxigenin
Apocymarin
CAS: 66-28-4
Molecular Formula: C23H32O6
5-beta-hydroxy-19-oxodigitoxigenin - Names and Identifiers
5-beta-hydroxy-19-oxodigitoxigenin - Physico-chemical Properties
| Molecular Formula | C23H32O6 |
| Molar Mass | 404.5 |
| Density | 1.432±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 169°C |
| Boling Point | 446.1°C (rough estimate) |
| Specific Rotation(α) | D25 +43.1° (c = 2.8 in methanol) |
| Solubility | Soluble in acetone, ethanol, chloroform, benzene and glacial acetic acid, almost insoluble in water, ether and petroleum ether. |
| Appearance | light yellow solid |
| pKa | 13.92±0.70(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.4593 (estimate) |
| MDL | MFCD00046266 |
5-beta-hydroxy-19-oxodigitoxigenin - Risk and Safety
| Hazard Symbols | T+ - Very toxic |
| Risk Codes | 26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | FH5425000 |
| Toxicity | LD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel) |
5-beta-hydroxy-19-oxodigitoxigenin - Introduction
Apoymarin (Apocymarin) is a natural compound extracted from Apocynum venetum. It is a white crystalline powder with a bitter taste.
Apocymarin has a certain application value in the field of medicine. It has been found to have antioxidant, anti-inflammatory, anti-cancer and anti-cardiovascular disease and other pharmacological activities. It can inhibit the growth and spread of tumor cells, and has certain potential for the treatment of malignant tumors such as lung cancer, breast cancer and liver cancer. In addition, Apocymarin also has the function of lowering blood lipids, lowering blood pressure and anti-platelet aggregation.
The preparation method of Apocymarin is more complicated. The total saponins are usually extracted from the poisonous whorl first, and then Apocymarin is obtained after repeated extraction and separation and purification. The specific preparation method can be adjusted according to different experimental conditions and requirements.
Regarding safety information, Apocymarin is a natural product and is generally considered to have a certain degree of safety. However, as a chemical substance, it is still necessary to follow the corresponding safety operation specifications when used. When performing experiments or applications, care should be taken to avoid contact with skin, eyes and mouth. At the same time, the toxicology of Apocymarin is still relatively limited, so it should be used with caution and follow the doctor's advice in large doses or for long-term use.
Apocymarin has a certain application value in the field of medicine. It has been found to have antioxidant, anti-inflammatory, anti-cancer and anti-cardiovascular disease and other pharmacological activities. It can inhibit the growth and spread of tumor cells, and has certain potential for the treatment of malignant tumors such as lung cancer, breast cancer and liver cancer. In addition, Apocymarin also has the function of lowering blood lipids, lowering blood pressure and anti-platelet aggregation.
The preparation method of Apocymarin is more complicated. The total saponins are usually extracted from the poisonous whorl first, and then Apocymarin is obtained after repeated extraction and separation and purification. The specific preparation method can be adjusted according to different experimental conditions and requirements.
Regarding safety information, Apocymarin is a natural product and is generally considered to have a certain degree of safety. However, as a chemical substance, it is still necessary to follow the corresponding safety operation specifications when used. When performing experiments or applications, care should be taken to avoid contact with skin, eyes and mouth. At the same time, the toxicology of Apocymarin is still relatively limited, so it should be used with caution and follow the doctor's advice in large doses or for long-term use.
Last Update：2024-04-09 20:52:54
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Spot supply
Product Name: Apocymarin Visit Supplier Webpage Request for quotationCAS: 66-28-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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