5-bromo-4-methyl-thiazol-2-amine
5-bromo-4-methyl-thiazol-2-amine
CAS: 3034-57-9
Molecular Formula: C4H5BrN2S
5-bromo-4-methyl-thiazol-2-amine - Names and Identifiers
5-bromo-4-methyl-thiazol-2-amine - Physico-chemical Properties
| Molecular Formula | C4H5BrN2S |
| Molar Mass | 193.06 |
| Density | 1.806±0.06 g/cm3(Predicted) |
| Melting Point | 105-108.5 °C (decomp) |
| Boling Point | 298.3±20.0 °C(Predicted) |
| Flash Point | 134.191°C |
| Solubility | DMSO (Sparingly) |
| Vapor Presure | 0.001mmHg at 25°C |
| Appearance | Solid |
| Color | Very Dark Brown |
| pKa | 4.55±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.661 |
5-bromo-4-methyl-thiazol-2-amine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
5-bromo-4-methyl-thiazol-2-amine - Introduction
It is an organic compound with the chemical formula C5H6BrN3S.
Its properties are as follows:
Appearance: White crystalline solid
Melting point: 116-119 ° C
Boiling point: 280-281 ° C
Density: 1.86g/cm³
The main use of the pill is as a pharmaceutical intermediate. It can be used in the pharmaceutical industry for the synthesis of antibiotics, anti-tumor drugs and pesticides and other compounds.
The method of preparation is generally synthesis by diazotization reaction. First, 2-bromo-5-methylthiazole and sodium nitrite are reacted under strong acid conditions to produce a nitroso compound. Then, under alkaline conditions, the nitroso compound is reduced to phosphinite.
Regarding safety information, it is an organic compound and needs to follow general laboratory safety practices when operating. It can be irritating to the skin, eyes and respiratory tract, so wear appropriate protective equipment. At the same time, it should be stored sealed and away from fire and oxidizing agents. If taken or touched by mistake, seek medical attention or consult a professional immediately.
Its properties are as follows:
Appearance: White crystalline solid
Melting point: 116-119 ° C
Boiling point: 280-281 ° C
Density: 1.86g/cm³
The main use of the pill is as a pharmaceutical intermediate. It can be used in the pharmaceutical industry for the synthesis of antibiotics, anti-tumor drugs and pesticides and other compounds.
The method of preparation is generally synthesis by diazotization reaction. First, 2-bromo-5-methylthiazole and sodium nitrite are reacted under strong acid conditions to produce a nitroso compound. Then, under alkaline conditions, the nitroso compound is reduced to phosphinite.
Regarding safety information, it is an organic compound and needs to follow general laboratory safety practices when operating. It can be irritating to the skin, eyes and respiratory tract, so wear appropriate protective equipment. At the same time, it should be stored sealed and away from fire and oxidizing agents. If taken or touched by mistake, seek medical attention or consult a professional immediately.
Last Update：2024-04-09 21:11:58
