5-bromo-6-(trifluoromethyl)pyrimidin-4(3H)-one

5-bromo-6-(trifluoromethyl)pyrimidin-4(3H)-one - Names and Identifiers

Name	4(1H)-Pyrimidinone, 5-bromo-6-(trifluoromethyl)-
Synonyms	5-broMo-6-(trifluoroMethyl)pyriMidin-4-ol 5-Bromo-6-trifluoromethyl-3H-pyrimidin-4-one 5-BroMo-6-(trifluoroMethyl)pyriMidin-4(1H)-one 5-bromo-6-(trifluoromethyl)-4(3H)-Pyrimidinone 5-bromo-6-(trifluoromethyl)pyrimidin-4(3H)-one 4(1H)-Pyrimidinone, 5-bromo-6-(trifluoromethyl)- 4(1H)-pyrimidinone, 5-bromo-6-(trifluoromethyl)- 4(3H)-Pyrimidinone, 5-bromo-6-(trifluoromethyl)-
CAS	126538-81-6

5-bromo-6-(trifluoromethyl)pyrimidin-4(3H)-one - Physico-chemical Properties

Molecular Formula	C5H2BrF3N2O
Molar Mass	242.98
Storage Condition	2-8°C

5-bromo-6-(trifluoromethyl)pyrimidin-4(3H)-one - Introduction

5-Bromo-6-trifluoromethyl-4-hydroxypyrimidine is an organic compound with the chemical formula C5H3BrF3N2O. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to white crystalline
-melting point: 150-153 ℃
-boiling point: 279-280 ℃
-Solubility: Soluble in most organic solvents such as ethanol and dichloromethane

Use:
-5-bromo-6-trifluoromethyl-4-hydroxypyrimidine can be used as a pharmaceutical intermediate for the synthesis of biologically active compounds.
-It can be used in drug research to synthesize anti-cancer drugs, antiviral drugs, etc.

Method:
-5-Bromo-6-trifluoromethyl-4-hydroxypyrimidine is usually synthesized by chemical synthesis methods. A common method of preparation is the reaction of 5-bromo-6-methoxypyrimidine with N,N-dimethylacetamide in the presence of hexafluoroacetone.

Safety Information:
-5-Bromo-6-trifluoromethyl-4-hydroxypyrimidine may be irritating to the eyes, skin and respiratory system. Wear appropriate personal protective equipment such as gloves, safety goggles and protective masks when handling or touching.
-Avoid inhaling its dust or solution during operation, and avoid contact with skin and eyes. In case of accidental contact, flush the affected area with plenty of water and seek medical help.
-Please store and handle the compound properly, avoid contact with flammable materials, and operate in a well-ventilated place.

Last Update：2024-04-09 15:17:51