5-chlorisatide - Names and Identifiers
Name | 5-Chloroisatin
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Synonyms | NSC 135811 5-chlorisatide 5-Chloroisatin AKOS BBS-00000996 TIMTEC-BB SBB003741 5-CHLOR-2,3-INDOLINDION Isatin, 5-chloro- (6CI) 5-CHLOROINDOLE-2,3-DIONE 5-CHLOR-2,3-DIOXOINDOLIN 5-Chloroindolin-2,3-dione 5-CHLORO-2,3-INDOLINEDIONE 5-CHLORO-1H-INDOLE-2,3-DIONE Indole-2,3-dione, 5-chloro- (7CI,8CI) 5-Chloroindolin-2,3-dione, 5-Chloro-1H-indole-2,3-dione
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CAS | 17630-76-1
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EINECS | 241-614-0 |
InChI | InChI=1/C8H4ClNO2/c9-4-1-2-6-5(3-4)7(11)8(12)10-6/h1-3H,(H,10,11,12) |
5-chlorisatide - Physico-chemical Properties
Molecular Formula | C8H4ClNO2
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Molar Mass | 181.58 |
Density | 1.3743 (rough estimate) |
Melting Point | 254-258 °C (lit.) |
Water Solubility | insoluble |
Appearance | Pale yellow powder |
BRN | 383759 |
pKa | 8.65±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.5560 (estimate) |
MDL | MFCD00014567 |
Physical and Chemical Properties | Appearance: yellow crystal Melting Point: 247-252 ℃ |
5-chlorisatide - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
HS Code | 29339900 |
Hazard Note | Irritant |
5-chlorisatide - Introduction
5-Chloroisatin is an organic compound with the chemical formula C16H8Cl2N2O2. It is a red compound, commonly in the form of red needle crystals. The following is a description of the nature, use, preparation and safety information of 5-Chloroisatin:
Nature:
-Appearance: 5-Chloroisatin is a red needle-like crystal.
-Melting point: Melting point is about 297-299 ° C.
-Solubility: insoluble in water, but soluble in organic solvents such as alcohol, ether and dichloromethane.
Use:
-Biological research: 5-Chloroisatin is commonly used as a biological dye, such as the nucleus, cytoplasm and cell membrane stain.
-Culture and art: Due to its bright red color, 5-Chloroisatin is also used as an ingredient in dyes, pigments and inks.
Method:
- 5-Chloroisatin can be prepared by acetylation of cyanide 4,5-dichloro-diamino acid. First, 4,5-dichloro-diamino cyanide is reacted with acetic anhydride to form 4,5-dichloro-diaminoacetate cyanide. This intermediate is then reacted with cyanobromide to give cyano 4,5-dichloro-diaminoacetate. Finally, hydrogenation of this intermediate under basic conditions gives 5-Chloroisatin.
Safety Information:
- 5-Chloroisatin is non-toxic to humans. However, as a chemical substance, when it comes into contact with the skin or eyes, it should be rinsed immediately with plenty of water.
-During the operation of 5-Chloroisatin or its preparation, care should be taken to avoid inhaling its powder or solution to avoid irritation to the respiratory system.
-When storing or handling 5-Chloroisatin, avoid contact with oxidants, strong acids or strong bases to avoid dangerous reactions.
Please note that for the use or handling of chemicals, laboratory or professional guidance is recommended.
Last Update:2024-04-10 22:29:15