5-chloro-2-fluoro-4-methyl-pyridine
5-chloro-2-fluoro-4-methyl-pyridine
CAS: 884494-88-6
Molecular Formula: C6H5ClFN
5-chloro-2-fluoro-4-methyl-pyridine - Names and Identifiers
| Name | 5-chloro-2-fluoro-4-methyl-pyridine |
| Synonyms | 5-Chloro-2-fluoro-4-picoline 5-CHLORO-2-FLUORO-4-PICOLINE 2-Fluoro-4-methyl-5-chloropyridine 5-Chloro-2-fluoro-4-methylpyridine 5-chloro-2-fluoro-4-methyl-pyridine Pyridine, 5-chloro-2-fluoro-4-methyl- pyridine, 5-chloro-2-fluoro-4-methyl- |
| CAS | 884494-88-6 |
| InChI | InChI=1/C6H5ClFN/c1-4-2-6(8)9-3-5(4)7/h2-3H,1H3 |
5-chloro-2-fluoro-4-methyl-pyridine - Physico-chemical Properties
| Molecular Formula | C6H5ClFN |
| Molar Mass | 145.56 |
| Density | 1.264g/cm3 |
| Boling Point | 190.4°C at 760 mmHg |
| Flash Point | 69°C |
| Vapor Presure | 0.752mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.503 |
5-chloro-2-fluoro-4-methyl-pyridine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| Hazard Class | IRRITANT |
5-chloro-2-fluoro-4-methyl-pyridine - Introduction
It is an organic compound with a chemical formula of C6H5ClFN and a molecular weight of 141.56g/mol.
The compound has the following properties:
-Appearance: Colorless to light yellow liquid.
-Insoluble: Insoluble in water, soluble in non-polar solvents such as ethanol and dichloromethane.
-Melting point:-32°C
-Boiling Point: 129-130°C
It has a wide range of applications in the field of medicine and pesticides:
-Pharmaceutical field: It can be used to synthesize biologically active compounds as pharmaceutical intermediates.
-Pesticide field: can be used as pesticides and herbicides.
Methods of Preparation:
The commonly used synthesis method is to prepare 2-chloro-4-methylpyridine by fluorination. The reaction uses hydrogen fluoride as a fluorinating reagent. The reaction conditions are usually carried out at high temperature.
Safety Information:
-is an organic compound, which has a certain toxicity and should be safe when used.
-Contact with skin or inhalation of the substance may cause irritation, and prolonged exposure should be avoided.
-Wear protective gloves, goggles and protective clothing during operation and maintain a well-ventilated workplace.
-If taken by mistake or by mistake, seek medical attention immediately and bring packaging or labels.
-Observe local environmental regulations when disposing of waste.
The compound has the following properties:
-Appearance: Colorless to light yellow liquid.
-Insoluble: Insoluble in water, soluble in non-polar solvents such as ethanol and dichloromethane.
-Melting point:-32°C
-Boiling Point: 129-130°C
It has a wide range of applications in the field of medicine and pesticides:
-Pharmaceutical field: It can be used to synthesize biologically active compounds as pharmaceutical intermediates.
-Pesticide field: can be used as pesticides and herbicides.
Methods of Preparation:
The commonly used synthesis method is to prepare 2-chloro-4-methylpyridine by fluorination. The reaction uses hydrogen fluoride as a fluorinating reagent. The reaction conditions are usually carried out at high temperature.
Safety Information:
-is an organic compound, which has a certain toxicity and should be safe when used.
-Contact with skin or inhalation of the substance may cause irritation, and prolonged exposure should be avoided.
-Wear protective gloves, goggles and protective clothing during operation and maintain a well-ventilated workplace.
-If taken by mistake or by mistake, seek medical attention immediately and bring packaging or labels.
-Observe local environmental regulations when disposing of waste.
Last Update：2024-04-09 02:00:48
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CAS: 884494-88-6
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CAS: 884494-88-6
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