5-chloro-2H-indazole-3-carboxaldehyde

5-chloro-2H-indazole-3-carboxaldehyde - Names and Identifiers

Name	5-CHLORO INDAZOLE-3-CARBOXALDEHYDE
Synonyms	5-Chloro-3-(1H)indazole 5-CHLORO INDAZOLE-3-CARBOXALDEHYDE 5-CHLORO-1H-INDAZOLE-3-CARBALDEHYDE 5-chloro-2H-indazole-3-carbaldehyde 5-Chloro-1H-indazole-3-carbaldehyde 5-chloro-2H-indazole-3-carboxaldehyde 5-CHLORO-3-(1H)INDAZOLE CARBOXALDEHYDE 1H-Indazole-3-carboxaldehyde, 5-chloro-
CAS	102735-84-2
EINECS	1806241-263-5
InChI	InChI=1/C8H5ClN2O/c9-5-1-2-7-6(3-5)8(4-12)11-10-7/h1-4H,(H,10,11)

5-chloro-2H-indazole-3-carboxaldehyde - Physico-chemical Properties

Molecular Formula	C8H5ClN2O
Molar Mass	180.59
Density	1.521±0.06 g/cm3(Predicted)
Boling Point	391.7±22.0 °C(Predicted)
Flash Point	190.691°C
Vapor Presure	0mmHg at 25°C
pKa	10.85±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.748

5-chloro-2H-indazole-3-carboxaldehyde - Risk and Safety

HS Code

29339900

5-chloro-2H-indazole-3-carboxaldehyde - Introduction

5-Chloro-3-aldo-1H-indazole is an organic compound with the chemical formula C8H4ClN2O. It is a yellow crystalline powder, hardly soluble in water, soluble in organic solvents such as ethanol and chloroform.

5-Chloro-3-aldo-1H-indazole has many applications:
-Pharmaceutical field: It is an important intermediate for the synthesis of various drugs, such as anti-tumor drugs, anti-inflammatory drugs and antibiotics.
-Pesticide field: It can be used as a raw material for fungicides and pesticides.
-Dye field: It can be used as a dye precursor for dyeing cotton, wool and leather.

The methods for preparing 5-chloro-3-aldehyde -1H-indazole mainly include the following:
1. Indazole and aldehyde reaction: Indazole and aldehyde are reacted under appropriate conditions to generate 5-chloro-3-aldehyde -1H-indazole.
2. acylation reaction: the indazole is reacted with an acylating reagent (such as acid chloride) to generate acylated indazole, which is then subjected to chlorination reaction to obtain 5-chloro -3-aldehyde -1H-indazole.

Regarding the safety information of 5-chloro-3-aldo-1H-indazole, it is a chemical and needs to pay attention to the following aspects:
1. effects on the human body: the substance may cause irritation to the human respiratory system, eyes and skin. Wash with plenty of water as soon as possible after contact. Avoid inhaling dust and wear appropriate protective equipment.
2. storage and handling: it should be stored in a sealed container, avoid exposure to sunlight and open flame. Should be handled in a well-ventilated place, away from fire.
3. waste disposal: according to local laws and regulations, the correct disposal of waste, do not dump.

When handling 5-chloro-3-aldo-1H-indazole, it should be handled in accordance with safe operating procedures, and stored and handled in accordance with relevant regulations.

Last Update：2024-04-09 19:05:44