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5-fluoro-o-anisidine

5-Fluoro-2-methoxyaniline

CAS: 1978-39-8

Molecular Formula: C7H8FNO

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5-fluoro-o-anisidine - Names and Identifiers

Name 5-Fluoro-2-methoxyaniline
Synonyms 5-fluoro-o-anisidine
2-amino-4-fluoroanisole
5-Fluoro-2-methoxyaniline
5-fluoro-2-methoxybenzenamine
2-amino-4-fluoro-1-methoxybenzene
2-Amino-4-fluoroanisole, 5-Fluoro-o-anisidine
2-AMino-4-fluoroanisole[5-Fluoro-2-Methoxyaniline]
2-Amino-4-fluoroanisole5-Fluoro-o-anisidine2-Amino-4-fluoro-1-methoxybenzene
2-Amino-4-fluoroanisole, 5-Fluoro-2-methoxybenzenamine, 5-Fluoro-o-anisidine
CAS 1978-39-8
EINECS 206-939-4
InChI InChI=1/C7H8FNO/c1-10-7-3-2-5(8)4-6(7)9/h2-4H,9H2,1H3

5-fluoro-o-anisidine - Physico-chemical Properties

Molecular FormulaC7H8FNO
Molar Mass141.14
Density1.1981 g/mL at 25 °C
Melting Point3 °C
Boling Point90 °C/760 mmHg
Flash Point109°C
Vapor Presure0.0532mmHg at 25°C
Appearanceclear liquid
ColorColorless to Light yellow to Light orange
pKa3.52±0.10(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Room temperature
Refractive Indexn20/D 1.5438

5-fluoro-o-anisidine - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk CodesR22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDsUN 2810 6.1/PG III
WGK Germany3
Hazard Class6.1
Packing GroupIII

5-fluoro-o-anisidine - Introduction

5-Fluoro-2-methoxyaniline, chemical formula C7H8FNO, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: colorless or slightly yellow crystal.
2. Melting Point: about 58-62 ℃.
3. Boiling point: About 203 ℃.
4. Density: 1.149 g/mL.
5. Solubility: Soluble in some organic solvents, such as ethanol and chloroform.

Use:
1. 5-Fluoro-2-methoxyaniline is a common intermediate in organic synthesis. It plays an important role in the preparation of other organic compounds.
2. The compound is also used as an intermediate in the pharmaceutical field, mainly for the synthesis of drugs.

Method:
A common method for preparing 5-Fluoro-2-methoxyaniline is as follows:
1.2-fluoro-cresol is generated by the reaction of phenol with sodium hydrogen 2-fluoromethanesulfonate.
2. 2-Fluoro-cresol is then reacted with methoxy bromide to obtain 5-Fluoro-2-methoxyaniline.

Safety Information:
1. 5-Fluoro-2-methoxyaniline is an organic fluorine compound and should be handled with caution.
2. When operating should follow the safety procedures, wear appropriate personal protective equipment, such as gloves and safety glasses.
3. Avoid inhaling its vapors or contact with skin and eyes.
4. When storing, it should be stored in a closed container, away from fire and oxidant.

Please note that before using or handling 5-Fluoro-2-methoxyaniline, please refer to the laboratory chemical safety manual and follow the relevant safety operating procedures.
Last Update:2024-04-09 15:17:54
5-fluoro-o-anisidine
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Tel: +86-17551318830
Email: r@reformchem.com­
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Jiangsu Pules Biotechnology Co.,Ltd.
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CAS: 1978-39-8
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Email: pules.cn@gmail.com
Mobile: +86-17551318830
SKYRUN INDUSTRIAL CO.,LTD
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: 5-Fluoro-2-methoxyaniline Visit Supplier Webpage Request for quotation
CAS: 1978-39-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: 5-Fluoro-2-methoxyaniline Visit Supplier Webpage Request for quotation
CAS: 1978-39-8
Tel: +86-18821248368
Email: Int06@meryer.com
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