Molecular Formula | C9H13NO3 |
Molar Mass | 183.2 |
Density | 1.1967 (rough estimate) |
Melting Point | 181°C |
Boling Point | 316.88°C (rough estimate) |
Storage Condition | 2-8℃ |
Refractive Index | 1.4760 (estimate) |
Physical and Chemical Properties | Crystallization. Melting point 181 ℃. |
Hazard Class | IRRITANT |
Reference Show more | 1. [IF=3.033] Jin-Peng Zhu et al."In vivo toxicity assessment of 4′-O-methylpyridoxine from Ginkgo biloba seeds: Growth, hematology, metabolism, and oxidative parameters."Toxicon. 2021 Oct;201:66 |
Plant Source: | ginkgo biloba |
Use | intermediate of vitamin B6. |
production method | cyclization with methoxyacetylacetone and ethyl cyanoacetate in the presence of ammonium hydroxide, produce 5-cyano-6-hydroxy-4-methoxymethyl-2-methylpyridine, then nitrated 5-cyano-6-hydroxy-4-methoxymethyl-2-methyl-3-nitropyridine, chlorination of 6-chloro-5-cyano-4-methoxymethyl-2-methyl-3-nitropyridine, the product was prepared by catalytic hydrogenation of 3-amino -5-aminomethyl-4-methoxymethyl-2-methylpyridine with palladium carbon, and finally diazotization of the amino group and hydrolysis. |