5-hydroxyfuran-3(2H)-one
4-hydroxyfuran-2(5H)-one
CAS: 541-57-1
Molecular Formula: C4H4O3
5-hydroxyfuran-3(2H)-one - Names and Identifiers
| Name | 4-hydroxyfuran-2(5H)-one |
| Synonyms | B-Tetronic acid BETA-TETRONIC ACID Tetronicacid,beta- 4-HYDROXYFURAN-2(5H)-ONE 4-hydroxyfuran-2(5H)-one 4-HYDROXY-2(5H)-FURANONE 5-hydroxyfuran-3(2H)-one 4-HYDROXY-2,5-DIHYDROFURAN-2-ONE 4-Hydroxy-2,5-dihydrofuran-2-one |
| CAS | 541-57-1 |
| EINECS | 208-785-3 |
| InChI | InChI=1/C4H4O3/c5-3-1-4(6)7-2-3/h1,5H,2H2 |
5-hydroxyfuran-3(2H)-one - Physico-chemical Properties
| Molecular Formula | C4H4O3 |
| Molar Mass | 100.07 |
| Density | 1.5510 |
| Melting Point | 135-137 °C |
| Boling Point | 316.03°C |
| Flash Point | 161.959°C |
| Water Solubility | soluble |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | Light yellow-beige |
| BRN | 108442 |
| pKa | 3.55±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4688 (estimate) |
5-hydroxyfuran-3(2H)-one - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29321900 |
| Hazard Class | IRRITANT |
5-hydroxyfuran-3(2H)-one - Introduction
4-hydroxyfuran-2(5H)-one, chemical formula C5H4O3, also known as 4-hydroxyfuran-2(5H)-one, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
- 4-hydroxyfuran-2(5H)-one is a colorless crystalline solid with a special taste at room temperature.
-Its molecular structure contains a hydroxyl group and a furan ring.
- 4-hydroxyfuran-2(5H)-one is soluble in water and in some organic solvents, such as ethanol and ether.
-It is a relatively stable compound and is not easy to decompose at room temperature.
Use:
- 4-hydroxyfuran-2(5H)-one can be used as a synthetic intermediate for food spices, and used to synthesize compounds with fruit or vanilla flavors.
-It can also be used to prepare some active compounds in the pharmaceutical field and used as a key intermediate in the drug treatment process.
Preparation Method:
- 4-hydroxyfuran-2(5H)-one can be obtained by reacting furan with hydrochloric acid. First, furan is reacted with hydrochloric acid to produce 4-chloro-2 (5H)-furanone. 4-hydroxyfuran-2(5H)-one is then produced by reacting 4-chloro-2 (5H)-furanone with sodium hydroxide.
Safety Information:
The toxicity of -4-hydroxyfuran-2(5H)-one is relatively low and there is no direct harm to the human body.
-When using 4-hydroxyfuran-2(5H)-one, care should be taken to avoid contact with eyes, skin and respiratory tract, and to do a good job of ventilation.
-Follow the correct operating procedures during use and wear appropriate safety equipment, such as gloves and goggles.
-When operating with 4-hydroxyfuran-2(5H)-one, follow appropriate protective measures and laboratory safety regulations.
Nature:
- 4-hydroxyfuran-2(5H)-one is a colorless crystalline solid with a special taste at room temperature.
-Its molecular structure contains a hydroxyl group and a furan ring.
- 4-hydroxyfuran-2(5H)-one is soluble in water and in some organic solvents, such as ethanol and ether.
-It is a relatively stable compound and is not easy to decompose at room temperature.
Use:
- 4-hydroxyfuran-2(5H)-one can be used as a synthetic intermediate for food spices, and used to synthesize compounds with fruit or vanilla flavors.
-It can also be used to prepare some active compounds in the pharmaceutical field and used as a key intermediate in the drug treatment process.
Preparation Method:
- 4-hydroxyfuran-2(5H)-one can be obtained by reacting furan with hydrochloric acid. First, furan is reacted with hydrochloric acid to produce 4-chloro-2 (5H)-furanone. 4-hydroxyfuran-2(5H)-one is then produced by reacting 4-chloro-2 (5H)-furanone with sodium hydroxide.
Safety Information:
The toxicity of -4-hydroxyfuran-2(5H)-one is relatively low and there is no direct harm to the human body.
-When using 4-hydroxyfuran-2(5H)-one, care should be taken to avoid contact with eyes, skin and respiratory tract, and to do a good job of ventilation.
-Follow the correct operating procedures during use and wear appropriate safety equipment, such as gloves and goggles.
-When operating with 4-hydroxyfuran-2(5H)-one, follow appropriate protective measures and laboratory safety regulations.
Last Update：2024-04-09 21:01:54
