5-isocyano-1H-indole
5-isocyano-1H-indole
CAS: 623163-58-6
Molecular Formula: C9H6N2
5-isocyano-1H-indole - Names and Identifiers
| Name | 5-isocyano-1H-indole |
| Synonyms | 5-ISOCYANOINDOL 5-isocyano-1H-indole 5-ISOCYANO-1H-INDOLE 1H-Indole, 5-isocyano- 1H-indole, 5-isocyano- |
| CAS | 623163-58-6 |
| InChI | InChI=1/C9H6N2/c1-10-8-2-3-9-7(6-8)4-5-11-9/h2-6,11H |
5-isocyano-1H-indole - Physico-chemical Properties
| Molecular Formula | C9H6N2 |
| Molar Mass | 142.16 |
| Melting Point | 92-93℃ |
5-isocyano-1H-indole - Introduction
5-isocyano-1H-indole is an organic compound with the chemical formula C9H6N2. Its molecule contains an indole ring and an isocyano group attached to the indole.
About nature:
1. Appearance: 5-isocyano-1H-indole is a yellow to red crystalline object.
2. melting point: about 135-137 degrees Celsius.
3. solubility: soluble in organic solvents such as ethanol, dichloromethane and chloroform, insoluble in water.
About Use:
1. reagent: 5-isocyano-1H-indole is commonly used as a reagent in organic synthesis, for example, it can be used in the preparation of pyrazole and indole derivatives.
2. fluorescent dye: due to its fluorescent properties, 5-isocyano-1H-indole can also be used as a raw material for fluorescent dyes.
About the preparation method:
In general, 5-isocyano-1H-indole can be prepared by the following steps: first, an ester is formed under the action of brominated indole and alaninol, and then, in the presence of this ester, an amidation reaction is performed with isocyanate to obtain 5-isocyano-1H-indole.
About safety information:
1. 5-isocyano-1H-indole is an organic compound, and it is necessary to pay attention to protective measures during operation, including wearing chemical protective gloves and goggles.
2. avoid inhalation or contact with skin, avoid taking by mistake.
3. during use, pay attention to good ventilation conditions to avoid inhalation or contact.
4. storage should avoid direct sunlight and high temperature environment, keep sealed.
About nature:
1. Appearance: 5-isocyano-1H-indole is a yellow to red crystalline object.
2. melting point: about 135-137 degrees Celsius.
3. solubility: soluble in organic solvents such as ethanol, dichloromethane and chloroform, insoluble in water.
About Use:
1. reagent: 5-isocyano-1H-indole is commonly used as a reagent in organic synthesis, for example, it can be used in the preparation of pyrazole and indole derivatives.
2. fluorescent dye: due to its fluorescent properties, 5-isocyano-1H-indole can also be used as a raw material for fluorescent dyes.
About the preparation method:
In general, 5-isocyano-1H-indole can be prepared by the following steps: first, an ester is formed under the action of brominated indole and alaninol, and then, in the presence of this ester, an amidation reaction is performed with isocyanate to obtain 5-isocyano-1H-indole.
About safety information:
1. 5-isocyano-1H-indole is an organic compound, and it is necessary to pay attention to protective measures during operation, including wearing chemical protective gloves and goggles.
2. avoid inhalation or contact with skin, avoid taking by mistake.
3. during use, pay attention to good ventilation conditions to avoid inhalation or contact.
4. storage should avoid direct sunlight and high temperature environment, keep sealed.
Last Update：2024-04-10 22:29:15
