5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-ol
5-Methyl-s-triazolo[1,5-a]pyrimidin-7-ol
CAS: 2503-56-2
Molecular Formula: C6H6N4O
5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-ol - Names and Identifiers
5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-ol - Physico-chemical Properties
| Molecular Formula | C6H6N4O |
| Molar Mass | 150.14 |
| Density | 1.3471 (rough estimate) |
| Melting Point | 280-283°C(lit.) |
| Boling Point | 271.66°C (rough estimate) |
| Water Solubility | INSOLUBLE IN COLD WATER |
| Appearance | White |
| BRN | 609440 |
| pKa | 1.14±0.53(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6700 (estimate) |
| MDL | MFCD00005555 |
| Physical and Chemical Properties | 280-283°C |
5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-ol - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 1 |
| RTECS | XZ6133300 |
| FLUKA BRAND F CODES | 9 |
| TSCA | Yes |
| Hazard Note | Harmful |
5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-ol - Reference Information
| chemical properties | the melting point of the product is 281-283 ℃. |
| use | 7-hydroxy -5-methyl -1,3,4-triazinolizine is used as an intermediate of the drug zolazepam, and can also be used as an antifogging agent for negatives. 7-hydroxy -5-methyl [1,2,4] triazolo [1,5-a] pyrimidine can be used as a reactant to prepare triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor, which has strong and selective activity against malaria parasite Plasmodium falciparum. Used for the synthesis of ruthenium (II)-Hmtpo complex; synthesis of dihydroorose dehydrogenase inhibitors with antimalarial activity; synthesis of Vilsmeier reaction reagents with conjugated carbocyclic and heterocyclic rings; used for investigation The pharmacological activity caused by the connection with HIV TAR RNA; the additive used to study the space charge layer in silver bromide microcrystals |
| production method | this product is obtained by refluxing 3-amino -1,2, 4-triazole and ethyl acetoacetate in glacial acetic acid for 4 hours. |
| NIST chemical information | The information is: webbook.nist.gov provides (external link) |
| EPA chemical information | The information is: offered by ofmpub.epa.gov (external link) |
Last Update：2024-04-09 20:49:11
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Product Name: 5-Methyl-1,2,4-Triazolo[1,5-a]Pyrimidin-7-ol Visit Supplier Webpage Request for quotation
CAS: 2503-56-2
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CAS: 2503-56-2
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