5-phenyl-2-piperidinone
5-Phenylpiperidin-2-one
CAS: 3973-63-5
Molecular Formula: C11H13NO
5-phenyl-2-piperidinone - Names and Identifiers
| Name | 5-Phenylpiperidin-2-one |
| Synonyms | 5-phenyl-2-piperidone 5-Phenylpiperidin-2-one 5-phenyl-2-piperidinone 2-Piperidinone, 5-phenyl- 4-PHENYL-DELTA-VALEROLACTAM |
| CAS | 3973-63-5 |
5-phenyl-2-piperidinone - Physico-chemical Properties
| Molecular Formula | C11H13NO |
| Molar Mass | 175.23 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD02179047 |
5-phenyl-2-piperidinone - Risk and Safety
| Hazard Class | IRRITANT |
5-phenyl-2-piperidinone - Introduction
5-Phenylpiperidin-2-one, also known as 5-PP (5-Phenylpiperidin-2-one), is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C13H15NO
-Molecular weight: 201.26g/mol
-Melting point: 80-82°C
-Boiling point: 277-279°C
-Soluble: Soluble in alcohol and chloroform, insoluble in water
Use:
- 5-Phenylpiperidin-2-one is an important intermediate for the synthesis of drugs and is commonly used in the preparation of drugs and biologically active molecules.
-It is widely used in the field of medicine for research and development of antidepressant, anxiolytic, analgesic and antipsychotic drugs.
-In addition, 5-Phenylpiperidin-2-one also has some research uses, such as for the synthesis of anti-tumor drugs.
Preparation Method:
-The common synthesis method is through the reaction of acetophenone and piperidine. The specific steps are as follows:
1. Acetophenone and a certain amount of piperidine were added to the reaction vessel under anhydrous environment.
2. Slowly add aqueous sodium hydroxide solution at low temperature.
3. after the reaction, the hydrolysis is precipitated, and the pure product is obtained by carbon tetrachloride and suction filtration.
Safety Information:
- 5-Phenylpiperidin-2-one is a chemical that is potentially chemically hazardous.
-Observe relevant safety practices during handling and use, such as wearing appropriate protective equipment (e. g. gloves, glasses and lab coats).
-Avoid prolonged contact with skin, inhalation of gas or ingestion, etc. In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
-When storing and handling, you should comply with relevant regulations and place it in a safe and controllable place, away from fire and flammable materials.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C13H15NO
-Molecular weight: 201.26g/mol
-Melting point: 80-82°C
-Boiling point: 277-279°C
-Soluble: Soluble in alcohol and chloroform, insoluble in water
Use:
- 5-Phenylpiperidin-2-one is an important intermediate for the synthesis of drugs and is commonly used in the preparation of drugs and biologically active molecules.
-It is widely used in the field of medicine for research and development of antidepressant, anxiolytic, analgesic and antipsychotic drugs.
-In addition, 5-Phenylpiperidin-2-one also has some research uses, such as for the synthesis of anti-tumor drugs.
Preparation Method:
-The common synthesis method is through the reaction of acetophenone and piperidine. The specific steps are as follows:
1. Acetophenone and a certain amount of piperidine were added to the reaction vessel under anhydrous environment.
2. Slowly add aqueous sodium hydroxide solution at low temperature.
3. after the reaction, the hydrolysis is precipitated, and the pure product is obtained by carbon tetrachloride and suction filtration.
Safety Information:
- 5-Phenylpiperidin-2-one is a chemical that is potentially chemically hazardous.
-Observe relevant safety practices during handling and use, such as wearing appropriate protective equipment (e. g. gloves, glasses and lab coats).
-Avoid prolonged contact with skin, inhalation of gas or ingestion, etc. In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
-When storing and handling, you should comply with relevant regulations and place it in a safe and controllable place, away from fire and flammable materials.
Last Update：2024-04-09 15:18:09
