5-trifluoromethyl-pyridine-2-carbonitrile

5-trifluoromethyl-pyridine-2-carbonitrile - Names and Identifiers

Name	5-(trifluoromethyl)pyridine-2-carbonitrile
Synonyms	T6NJ BCN EXFFF 2-Cyano-5-(trifluoromethyl)pyridine 5-trifluoromethyl-pyridine-2-carbonitrile 5-(TrifluoroMethyl)-2-pyridinecarbonitrile 5-(trifluoromethyl)pyridine-2-carbonitrile 5-(Trifluoromethyl)-2-pyridinecarbonitrile 5-(Trifluoromethyl)pyridine-2-carbonitrile 2-Pyridinecarbonitrile, 5-(trifluoromethyl)- (5-Trifluoromethyl-pyridin-2-yl)-acetonitril (5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-ACETONITRILE 2-(5-(TRIFLUOROMETHYL)PYRIDIN-2-YL)ACETONITRILE 2-Cyano-5-(trifluoromethyl)pyridine, 5-(Trifluoromethyl)picolinonitrile
CAS	95727-86-9
EINECS	145-869-9
InChI	InChI=1/C7H3F3N2/c8-7(9,10)5-1-2-6(3-11)12-4-5/h1-2,4H

5-trifluoromethyl-pyridine-2-carbonitrile - Physico-chemical Properties

Molecular Formula	C7H3F3N2
Molar Mass	172.11
Density	1.37±0.1 g/cm3(Predicted)
Boling Point	232.3±40.0 °C(Predicted)
Flash Point	94.3°C
Water Solubility	Slightly soluble in water.
Vapor Presure	0.0595mmHg at 25°C
Appearance	Solid
pKa	-2.75±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.456

5-trifluoromethyl-pyridine-2-carbonitrile - Risk and Safety

UN IDs	UN3439
Hazard Class	6.1

5-trifluoromethyl-pyridine-2-carbonitrile - Introduction

5-(trifluoromethyl)pyridine-2-carbonitrile(5-(trifluoromethyl)pyridine-2-carbonitrile) is an organic compound with the chemical formula C7H2F3N.

Nature:
5-(trifluoromethyl)pyridine-2-carbonitrile is a colorless liquid with a unique smell. It has a density of about 1.34 g/mL and a boiling point of 162-165°C.

Use:
5-(trifluoromethyl)pyridine-2-carbonitrile is an important organic synthesis intermediate, which is widely used in medicine, pesticide, material science and other fields. It can be used to synthesize anticancer drugs, insecticides and some organic photoelectric materials.

Preparation Method:
5-(trifluoromethyl)pyridine-2-carbonitrile is prepared by various methods, mainly including the following:
1. by 2-cyano-5-bromomethylpyridine and trifluoromethyl bromide reaction.
2. 2-Cyano-5-methylpyridine is reacted with trifluoromethyl bromide in the presence of sodium chloride at high temperature.

Safety Information:
Because 5-(trifluoromethyl)pyridine-2-carbonitrile has an irritating effect on the eyes, skin and respiratory tract, care should be taken to avoid contact when using it. If you come into contact with the substance, rinse immediately with plenty of water and seek medical help. In addition, it is also a flammable liquid and should be stored away from fire sources and high temperature environments, and pay attention to fire and explosion prevention. During use and storage, please follow the relevant safety practices.

Last Update：2024-04-09 19:05:53