5-叔丁基异噁唑-3-羧酸
5-tert-Butyl-3-isoxazolecarboxylic acid
CAS: 90607-21-9
Molecular Formula: C8H11NO3
5-叔丁基异噁唑-3-羧酸 - Names and Identifiers
5-叔丁基异噁唑-3-羧酸 - Physico-chemical Properties
| Molecular Formula | C8H11NO3 |
| Molar Mass | 169.18 |
| Density | 1.169±0.06 g/cm3(Predicted) |
| Boling Point | 303.5±30.0 °C(Predicted) |
| pKa | 3.49±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Sensitive | IRRITANT |
| MDL | MFCD07377301 |
5-叔丁基异噁唑-3-羧酸 - Risk and Safety
| Hazard Class | IRRITANT |
5-叔丁基异噁唑-3-羧酸 - Introduction
Acid is an organic compound with the chemical formula C10H15NO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: acid is a white crystalline solid.
-Melting point: Its melting point is about 133-137°C.
-Solubility: It is soluble in some organic solvents, such as ethanol, acetone and dichloromethane.
Use:
-the acid can be used as an organic synthesis intermediate for the synthesis of other complex compounds.
-It can also be used as a chemical reagent in the field of pesticides or pharmaceuticals.
Preparation Method:
Acid is usually prepared by the following steps:
1. Acetononitrile reacts with sulfonyl chloride to generate tert-butyl acyl acetone imine.
2. Under alkaline conditions, tert-butyl acyl acetonimine reacts with ammonia to generate 5-tert-butyl isoxazole-3-carboxamide.
3. Finally, 5-tert-butyl isoxazole-3-carboxamide is reacted with hydrochloric acid to obtain acid.
Safety Information:
-the acid may be irritating to the eyes, respiratory system and skin, so avoid contact during use.
-Good laboratory practices and personal protective measures should be taken during use, storage and handling.
-it should be kept away from high temperature and fire, stored in a cool, dry, well-ventilated place.
-Before use or disposal, consult relevant safety information and follow appropriate safety operating procedures.
Nature:
-Appearance: acid is a white crystalline solid.
-Melting point: Its melting point is about 133-137°C.
-Solubility: It is soluble in some organic solvents, such as ethanol, acetone and dichloromethane.
Use:
-the acid can be used as an organic synthesis intermediate for the synthesis of other complex compounds.
-It can also be used as a chemical reagent in the field of pesticides or pharmaceuticals.
Preparation Method:
Acid is usually prepared by the following steps:
1. Acetononitrile reacts with sulfonyl chloride to generate tert-butyl acyl acetone imine.
2. Under alkaline conditions, tert-butyl acyl acetonimine reacts with ammonia to generate 5-tert-butyl isoxazole-3-carboxamide.
3. Finally, 5-tert-butyl isoxazole-3-carboxamide is reacted with hydrochloric acid to obtain acid.
Safety Information:
-the acid may be irritating to the eyes, respiratory system and skin, so avoid contact during use.
-Good laboratory practices and personal protective measures should be taken during use, storage and handling.
-it should be kept away from high temperature and fire, stored in a cool, dry, well-ventilated place.
-Before use or disposal, consult relevant safety information and follow appropriate safety operating procedures.
Last Update：2024-04-09 21:00:56
