5-氯-2,4-二磺酰胺基苯胺
4-amino-6-chloro-1,3-benzenedisulfonamide
CAS: 121-30-2
Molecular Formula: C6H8ClN3O4S2
5-氯-2,4-二磺酰胺基苯胺 - Names and Identifiers
5-氯-2,4-二磺酰胺基苯胺 - Physico-chemical Properties
| Molecular Formula | C6H8ClN3O4S2 |
| Molar Mass | 285.73 |
| Density | 1.584 (estimate) |
| Melting Point | 257-261°C(lit.) |
| Boling Point | 614.4±65.0 °C(Predicted) |
| Flash Point | 325.4°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 4.98E-15mmHg at 25°C |
| Appearance | Crystallization |
| Color | White to off-white |
| Merck | 14,2076 |
| BRN | 1083877 |
| pKa | 9.24±0.60(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6100 (estimate) |
| MDL | MFCD00007933 |
| Physical and Chemical Properties | Melting point 257-261°C |
| Use | Used as pharmaceutical intermediates, can be used for the synthesis of hydrochlorothiazide and other raw materials |
5-氯-2,4-二磺酰胺基苯胺 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R23/24 - R33 - Danger of cumulative effects R20/21 - Harmful by inhalation and in contact with skin. |
| Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37 - Wear suitable protective clothing and gloves. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| HS Code | 29350090 |
| Hazard Class | IRRITANT |
5-氯-2,4-二磺酰胺基苯胺 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | intermediate of the drug dihydrochlorothiazide. As a pharmaceutical intermediate, it can be used to synthesize hydrochlorothiazide and other APIs |
| production method | m-chloroaniline is obtained by chlorosulfonation of chlorosulfonic acid and amination of liquid chlorine. |
Last Update：2024-04-09 15:16:47
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View History
5-氯-2,4-二磺酰胺基苯胺
METHYL DODECANOATE
(1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-4-...
2-Chloro-2-nitrosoadamantane
二苯胺磺酸钠(AR,IND)
3-[[3,5-双(三氟甲基)苯基]氨基]-4-[[(1R,2R)-2-(二戊基)环己基]氨基]-3-环丁烯-1,2-二酮
ETHYL 2-ETHYLBUTYRATE
1-Octadecanamine, N-octadecyl-
Polyurethane resin
Ethyl triphenyl phosphoniuM broMide (ETPB)
METHYL DODECANOATE
(1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-4-...
2-Chloro-2-nitrosoadamantane
二苯胺磺酸钠(AR,IND)
3-[[3,5-双(三氟甲基)苯基]氨基]-4-[[(1R,2R)-2-(二戊基)环己基]氨基]-3-环丁烯-1,2-二酮
ETHYL 2-ETHYLBUTYRATE
1-Octadecanamine, N-octadecyl-
Polyurethane resin
Ethyl triphenyl phosphoniuM broMide (ETPB)