5-氯-4-甲酰基-1-甲基-1H-吡唑-3-羧酸乙酯

5-氯-4-甲酰基-1-甲基-1H-吡唑-3-羧酸乙酯 - Names and Identifiers

Name	ethyl 5-chloro-4-formyl-1-methyl-pyrazole-3-carboxylate
Synonyms	ethyl 5-chloro-4-formyl-1-methyl-pyrazole-3-carboxylate ethyl 5-chloro-4-formyl-1-methyl-1H-pyrazole-3-carboxylate ETHYL 5-CHLORO-4-FORMYL-1-METHYL-1H-PYRAZOLE-3-CARBOXYLATE 1H-pyrazole-3-carboxylic acid, 5-chloro-4-forMyl-1-Methyl-, ethyl ester
CAS	946061-21-8
InChI	InChI=1/C8H9ClN2O3/c1-3-14-8(13)6-5(4-12)7(9)11(2)10-6/h4H,3H2,1-2H3

5-氯-4-甲酰基-1-甲基-1H-吡唑-3-羧酸乙酯 - Physico-chemical Properties

Molecular Formula	C8H9ClN2O3
Molar Mass	216.62
Density	1.37
Boling Point	356.1°C at 760 mmHg
Flash Point	169.1°C
Vapor Presure	3E-05mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.565

5-氯-4-甲酰基-1-甲基-1H-吡唑-3-羧酸乙酯 - Introduction

Ethyl (ethyl 5-chloro-4-formyl-1-methyl-1H-pyrazole-3-carboxylate) is an organic compound. The following is its nature, use, preparation and safety information:

Nature:
-Chemical formula: C9H9ClN2O3
-Molecular weight: 224.63g/mol
-Appearance: Colorless to light yellow crystal or powder
-Melting point: 132-136 degrees Celsius
-Solubility: Soluble in most organic solvents

Use:
Ethyl 5-chloro-4-formyl-1-methyl-1H-pyrazole-3-carboxylate has many uses in the chemical field, some of which include:
-Monomers as Reagents in Organic Synthesis
-Intermediates for the preparation of pyrazole drugs and pesticides
-for the synthesis of aromatic alcohols with high aldehyde content

Preparation Method:
The preparation of ethyl 5-chloro-4-formyl-1-methyl-1H-pyrazole-3-carboxylate can usually be completed by the following steps:
1. Chloroacetic anhydride reacts with 5-formyl -1-methyl -1H-pyrazole -3-carboxylic acid to generate 5-formyl -1-methyl -1H-pyrazole -3-carboxylic acid ester.
2. The product is reacted with ferrous chloride to undergo a substitution reaction to obtain 5-chloro -4-formyl -1-methyl -1H-pyrazole -3-carboxylate.
3. Finally, the resulting product was reacted with ethanol to obtain ethyl 5-chloro-4-formyl-1-methyl-1H-pyrazole-3-carboxylate.

Safety Information:
The safety information of ethyl 5-chloro-4-formyl-1-methyl-1H-pyrazole-3-carboxylate has not been fully studied and reported. However, appropriate personal protective measures, such as gloves, goggles and protective clothing, should be taken in accordance with the general recommendations for handling similar compounds. In addition, the operation should be carried out in a well-ventilated area and avoid contact with skin, eyes and respiratory tract. In case of accidental contact or misuse, seek medical attention immediately. Detailed safety information can be found in the safety data sheet of the chemical product concerned.

Last Update：2024-04-09 21:00:56