502496-21-1

502496-21-1 - Names and Identifiers

Name	[4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine hydrochloride
Synonyms	4-Fluoro-2-(trifluoromethyl)phenylhydrazine(HCl) 4-Fluoro-2-(trifluoromethyl)phenylhydrazine hydrochloride [4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine hydrochloride [4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine monohydrochloride 5-Fluoro-2-hydrazinobenzotrifluoride hydrochloride, 4-Fluoro-1-hydrazino-2-(trifluoromethyl)benzene hydrochloride
CAS	502496-21-1
InChI	InChI:1S/C7H6F4N2.ClH/c8-4-1-2-6(13-12)5(3-4)7(9,10)11;/h1-3,13H,12H2;1H

502496-21-1 - Physico-chemical Properties

Molecular Formula	C7H6F4N2.HCl
Molar Mass	230.59
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

502496-21-1 - Introduction

[4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine hydrochloride is an organic compound with the chemical formula C7H5F4N2 • HCl. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid
-Molecular weight: 248.58g/mol
-Melting point: 156-158°C
-Solubility: Slightly soluble in water, soluble in common organic solvents such as methanol and ethanol

Use:
[4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine hydrochloride has certain application value in the field of organic synthesis. It is often used as a fluorinated reagent and can participate in the coupling reaction of boron silicon, boron hydrogen and tin iodide. It can also be used to prepare specific ligands and transition metal complexes.

Preparation Method:
[4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine hydrochloride are generally prepared by the following steps:
1.4-fluoro-2-(trifluoromethyl) aniline is reacted with excess ammonia at room temperature.
2. Acetic acid was added dropwise to the reaction mixture to produce the product.
3. The product is reacted with hydrochloric acid to obtain [4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine hydrochloride.

Safety Information:
Note the following safety precautions when using the [4-Fluoro-2-(trifluoromethyl)phenyl]hydrazine hydrochloride:
-It may have irritating and damaging effects on the skin, eyes and respiratory system, and direct contact should be avoided.
-Wear appropriate protective gloves, eye/face protection and respiratory protection during operation.
-Operate in a well-ventilated place to avoid inhaling the gas and steam generated.
-Avoid contact with strong oxidants to prevent fire and explosion hazards.
-When storing and handling, isolate it from other chemicals and avoid exposure to moisture in the air.
-When handling or disposing of waste, follow local regulations and refer to relevant safety data.

Last Update：2024-04-10 22:29:15