Name | 4-Amino-2,5-dichlorophenol |
Synonyms | Lenvatinib Impurity 52 4-Amino-2,5-dichlorophenol 2,5-Dichloro-4-aminophenol Phenol, 4-amino-2,5-dichloro- |
CAS | 50392-39-7 |
InChI | InChI=1/C6H5Cl2NO/c7-3-2-6(10)4(8)1-5(3)9/h1-2,10H,9H2 |
Molecular Formula | C6H5Cl2NO |
Molar Mass | 178.02 |
Density | 1.560 |
Melting Point | 178-179 °C |
Boling Point | 296 °C |
Flash Point | 133 °C |
Vapor Presure | 0.001mmHg at 25°C |
Appearance | Bright yellow solid |
pKa | 7.81±0.23(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.661 |
Physical and Chemical Properties | This product is a solid crystal, m.p.178 ℃ ~ 179 ℃, insoluble in water, soluble in organic solvents, soluble in alcohol, ether and acetic acid. |
use | 2, 5-dichloro-4-aminophenol is an intermediate of the insecticide lice. |
production method | the preparation method is based on 2, 5-dichloro-4-aminobenzene ether as raw material, heated with iodide acid for 5 hours, cooled and filtered, dissolved in Na2SO2 aqueous solution, removed the remaining hydrogen iodide, then added ammonia water, precipitated and filtered to obtain the product. |