Name | Mitraphylline |
Synonyms | Rubradinin Mitraphyllin Mitraphylline Ajmalicine oxindole B 19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate (1S,4aS,5aS,6R,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester (1'S,3R,4'aS,5'aS,10'aR)-1,2,5',5'a,7',8',10',10'a-Octahydro-1'-methyl-2-oxospiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid methyl ester |
CAS | 509-80-8 |
EINECS | 208-106-0 |
Molecular Formula | C21H24N2O4 |
Molar Mass | 368.43 |
Density | 1.33 |
Melting Point | 265~266℃ |
Boling Point | 555.2±50.0 °C(Predicted) |
Solubility | Soluble in ethanol, chloroform and acetic acid |
Appearance | Powder |
pKa | 13.56±0.60(Predicted) |
Storage Condition | 2-8°C |
biological activity | The major pentacyclic indole alkaloids in Uncaria villosa. Mitraphyline inhibits lipopolysaccharide-mediated primary human neutrophil activation. |