5111-69-3
5-methoxyindan
CAS: 5111-69-3
Molecular Formula: C10H12O
5111-69-3 - Names and Identifiers
| Name | 5-methoxyindan |
| Synonyms | 5-methoxyindan 5-METHOXYINDAN 5-methoxyindane 5-methoxy-2,3-dihydro-1H-indene 1H-Indene, 2,3-dihydro-5-methoxy- |
| CAS | 5111-69-3 |
| InChI | InChI=1/C10H12O/c1-11-10-6-5-8-3-2-4-9(8)7-10/h5-7H,2-4H2,1H3 |
5111-69-3 - Physico-chemical Properties
| Molecular Formula | C10H12O |
| Molar Mass | 148.2 |
| Density | 1.023 g/mL at 25 °C (lit.) |
| Boling Point | 143-145 °C/60 mmHg (lit.) |
| Flash Point | 209°F |
| Vapor Presure | 0.0924mmHg at 25°C |
| Refractive Index | n20/D 1.544(lit.) |
5111-69-3 - Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
5111-69-3 - Introduction
5-Methoxyindan (5-Methoxyindan) is an organic compound whose chemical structure contains an indan structure and a methoxy group. The following is a description of the nature, use, formulation and safety information of 5-methoxyindan:
Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 40-42°C
-Boiling point: about 225-230°C
-Solubility: insoluble in water, soluble in organic solvents such as ethanol, dimethylformamide
Use:
-Drug synthesis: 5-methoxyindan can be used as an intermediate in drug synthesis, especially in the synthesis of compounds with antipsychotic activity.
-Scientific research: 5-methoxyindan may be used in the field of chemical research, such as as a reagent or participating in organic synthesis reactions.
Preparation Method:
5-methoxyindan can be synthesized by methods such as phenyl/alkyl Grignard reaction (Benzyl/Allyl Grignard Reaction) or Friedel-Crafts reaction (Fu-Kok Reaction). The specific preparation method may vary slightly due to the research purpose or application field, please refer to the corresponding experimental details in the specific synthesis scheme.
Safety Information:
In the operation and handling of any chemical, appropriate safety measures need to be taken, and 5-methoxyindan is no exception. Although there is no specific security risk report, the following general security guidelines should be followed:
-Avoid inhalation, ingestion or skin contact
-Use appropriate protective equipment, such as lab gloves and safety glasses
-Operate in a well-ventilated area
-When storing and handling, avoid storing with oxidants and flammable materials
This information is for informational purposes only and be sure to consult the relevant literature and safety data sheets prior to specific applications or studies.
Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 40-42°C
-Boiling point: about 225-230°C
-Solubility: insoluble in water, soluble in organic solvents such as ethanol, dimethylformamide
Use:
-Drug synthesis: 5-methoxyindan can be used as an intermediate in drug synthesis, especially in the synthesis of compounds with antipsychotic activity.
-Scientific research: 5-methoxyindan may be used in the field of chemical research, such as as a reagent or participating in organic synthesis reactions.
Preparation Method:
5-methoxyindan can be synthesized by methods such as phenyl/alkyl Grignard reaction (Benzyl/Allyl Grignard Reaction) or Friedel-Crafts reaction (Fu-Kok Reaction). The specific preparation method may vary slightly due to the research purpose or application field, please refer to the corresponding experimental details in the specific synthesis scheme.
Safety Information:
In the operation and handling of any chemical, appropriate safety measures need to be taken, and 5-methoxyindan is no exception. Although there is no specific security risk report, the following general security guidelines should be followed:
-Avoid inhalation, ingestion or skin contact
-Use appropriate protective equipment, such as lab gloves and safety glasses
-Operate in a well-ventilated area
-When storing and handling, avoid storing with oxidants and flammable materials
This information is for informational purposes only and be sure to consult the relevant literature and safety data sheets prior to specific applications or studies.
Last Update：2024-04-09 15:17:58
