51307-59-6

51307-59-6 - Names and Identifiers

Name	N-Hydroxy-1-(4-methoxyphenyl)methanamine
Synonyms	N-Hydroxy-4-methoxybenzylamine N-(p-Methoxybenzyl)hydroxylamine N-(4-Methoxybenzyl)hydroxylaMine N-hydroxy(4-methoxyphenyl)methanamine N-[(4-methoxyphenyl)methyl]hydroxylamine N-Hydroxy-1-(4-Methoxyphenyl)MethanaMine N-Hydroxy-1-(4-methoxyphenyl)methanamine Benzenemethanamine, N-hydroxy-4-methoxy- N-hydroxy(4-methoxyphenyl)methanamine hydrochloride
CAS	51307-59-6
InChI	InChI=1S/C8H11NO2/c1-11-8-4-2-7(3-5-8)6-9-10/h2-5,9-10H,6H2,1H3

51307-59-6 - Physico-chemical Properties

Molecular Formula	C8H11NO2
Molar Mass	153.18
Density	1.125±0.06 g/cm3(Predicted)
Boling Point	301.5±44.0 °C(Predicted)
pKa	13.26±0.30(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C

51307-59-6 - Introduction

N-Hydroxy-1-(4-methoxyphenyl)methanamine, the chemical formula is C9H13NO2 • HCl, is a white solid powder. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: N-Hydroxy-1-(4-methoxyphenyl)methanamine as a white crystalline solid.
-Melting point: about 150-155°C.
-Solubility: Soluble in water and some organic solvents, such as alcohols and ethers.

Use:
- N-Hydroxy-1-(4-methoxyphenyl)methanamine can be used as an intermediate in organic synthesis for the synthesis of drugs and other compounds.
-It can also be used as a catalyst for some catalytic reactions.

Preparation Method:
N-Hydroxy-1-(4-methoxyphenyl)methanamine can be prepared by reacting p-methoxybenzylamine with sodium nitrite under acidic conditions. Specific steps are as follows:
1. Under acidic conditions such as acetic acid, sodium nitrite is added to the p-methoxybenzylamine solution, and the reaction is stirred.
2. After the reaction is completed, the product is crystallized by cooling to obtain N-Hydroxy-1-(4-methoxyphenyl)methanamine.

Safety Information:
N-Hydroxy-1-(4-methoxyphenyl)methanamine are generally relatively safe under normal conditions of use. However, as a chemical, it still needs to be handled and stored properly. Here are some safety considerations:
-Avoid contact with skin, eyes and respiratory tract: Use chemical protective gloves, goggles and respiratory protective equipment.
-Avoid inhaling dust and avoid ingestion.
-Follow normal laboratory safety operations and comply with relevant regulations and regulations when using and handling.
-Store according to product instructions and avoid contact with incompatible substances.
-Waste disposal should follow local waste management regulations.

Last Update：2024-04-09 20:45:29