51546-12-4
2-氯-5-(甲硫基)苯甲酸
CAS: 51546-12-4
Molecular Formula: C8H7ClO2S
51546-12-4 - Names and Identifiers
51546-12-4 - Physico-chemical Properties
| Molecular Formula | C8H7ClO2S |
| Molar Mass | 202.66 |
| Density | 1.42 |
| Melting Point | 136-137 °C (lit.) |
| Boling Point | 342.4±32.0 °C(Predicted) |
| pKa | 2.74±0.25(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
51546-12-4 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
51546-12-4 - Introduction
2-Chloro-5-(methylthio) benzoic acid is an organic compound with the chemical formula C8H7ClOS, often abbreviated as CMSPA.
Nature:
-Appearance: Colorless crystalline solid
-melting point: about 80-82 ℃
-Boiling point: about 286 ℃
-Solubility: Soluble in organic solvents, insoluble in water
-Odor: Has a slight odor of sulfur
Use:
-Chemical reagents: CMSPA can be used for important intermediates in organic synthesis, such as the synthesis of heterocyclic compounds.
-Pharmaceutical field: CMSPA can also be used as an intermediate for certain drugs for the preparation of drugs containing benzoic acid groups.
-Dye industry: CMSPA can be used as a dye intermediate for the synthesis of dyes.
Preparation Method:
The preparation of CMSPA is usually obtained by reacting thiols with 2-chlorobenzoic acid. The specific reaction conditions can be optimized according to the experimental requirements.
Safety Information:
- CMSPA has a certain degree of irritation, please avoid contact with skin, eyes and respiratory tract, and equipped with appropriate protective measures, such as wearing protective glasses and gloves.
-Avoid coexistence with strong oxidants and strong bases to avoid dangerous reactions.
-storage should be sealed, in a well-ventilated place away from the fire and flammable storage.
Nature:
-Appearance: Colorless crystalline solid
-melting point: about 80-82 ℃
-Boiling point: about 286 ℃
-Solubility: Soluble in organic solvents, insoluble in water
-Odor: Has a slight odor of sulfur
Use:
-Chemical reagents: CMSPA can be used for important intermediates in organic synthesis, such as the synthesis of heterocyclic compounds.
-Pharmaceutical field: CMSPA can also be used as an intermediate for certain drugs for the preparation of drugs containing benzoic acid groups.
-Dye industry: CMSPA can be used as a dye intermediate for the synthesis of dyes.
Preparation Method:
The preparation of CMSPA is usually obtained by reacting thiols with 2-chlorobenzoic acid. The specific reaction conditions can be optimized according to the experimental requirements.
Safety Information:
- CMSPA has a certain degree of irritation, please avoid contact with skin, eyes and respiratory tract, and equipped with appropriate protective measures, such as wearing protective glasses and gloves.
-Avoid coexistence with strong oxidants and strong bases to avoid dangerous reactions.
-storage should be sealed, in a well-ventilated place away from the fire and flammable storage.
Last Update：2024-04-09 02:00:56
