517-43-1
SENNOSIDES
CAS: 517-43-1
Molecular Formula: C42H38O20
517-43-1 - Names and Identifiers
| Name | SENNOSIDES |
| Synonyms | SENNOSID SENNOSIDES Sennoside (8CI) MIXTURE OF SENNOSIDE A AND B 5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid 9,9',10,10'-Tetrahydro-4,4'-dihydroxy-5,5'-bis(β-D-glucopyranosyloxy)-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid 5,5'-Bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo[9,9'-bianthracene]-2,2'-dicarboxylic acid [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(b-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo- (9CI) |
| CAS | 517-43-1 |
| EINECS | 208-238-9 |
517-43-1 - Physico-chemical Properties
| Molecular Formula | C42H38O20 |
| Molar Mass | 862.75 |
| Density | 1.743 |
| Boling Point | 1144.8±65.0 °C(Predicted) |
| pKa | 3.31±0.40(Predicted) |
| Physical and Chemical Properties | Physicochemical properties sennoside is an equivalent mixture of the calcium salts of SennosideA and B extracted from SennosideB. This product has a stimulating effect on the large intestine wall, reflex to increase its peristalsis, causing defecation. It is suitable for constipation, especially for catharsis after taking anthelmintics. |
517-43-1 - Risk and Safety
| HS Code | 2938900000 |
517-43-1 - plant Salt containing senna glycoside and preparation method thereof
from titanium academic
Application (patent) number:
CN 201610242032
application date:
Apr 19, 2016
Public/Announcement Number:
CN 105876735 A
applicant (patent):
Wang Sheng
inventor:
National and provincial code:
Shandong; 37
Abstract:
The present invention provides a plant salt containing Senna glycosides, the plant salt comprising the following components: suaeda salsa extract, Nostoc flagelliforme powder, Veratrum orientalis powder, winter melon powder, raspberry extract, mushroom extract, senna glycosides. S. salsa extract, seaweed powder, powder Chuanxiong, melon pink, raspberry extract, mushroom extract, Fan Xie Ye glycosides. A preparation method of a plant salt containing Senna glycosides, the preparation method comprising a step of preparing an extract of suaeda salsa (L.), removal of heavy metals, and edible salt co-crystallization step. Containing sennodes preparation plants, preparation methods the preparation of S. Salicylextract step; S. salsa extract preparation step comprises raw material crushing, enzymatic hydrolysis, removal of heavy metals, and total edible salt crystallization step. The beneficial effects of the invention are as follows: the plant salt of the invention has obvious swelling-reducing effect, and the swelling-reducing experiment of mouse toe is carried out, at 6h, the swelling degree of the toe of the mice was only 49.1 ~ 57.9% of that of the mice not consuming the plant salt of the present invention, and the symptoms of lower band and white turbidity were obviously improved, and the effective rate of improving lower band was 85 ~ 93%; the effective rate of improving White turbidity was 92 ~ 96%; The symptoms of beriberi were obviously improved, and the effective rate of improving beriberi was 89 ~ 95%. The beneficial effects of the present, toe swelling in mice experiments, 6h toe when the swelling of mice not only edible plants salt mice of the present invention 49.1 ~ 57.9%; significant improvement in vaginal discharge, gonorrhea symptoms, improve vaginal discharge effective rate of 85 ~ 93%; improved clouding effective rate of 92 to 96%; significantly improved symptoms of beriberi, beriberi improvement of efficiency 89 to 95%.
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sovereignty:
1. A plant salt containing Senna glycosides, characterized in that: the plant salt comprises the following components: Suaeda extract, Nostoc flagelliforme powder, Veratrum orientalis powder, winter melon powder, raspberry extract, mushroom extract, senna glycosides.
Last Update：2024-01-02 23:10:35
517-43-1 - Role of Senna glycoside A in the intestine of mice
from hownet
Author:
Abstract:
sennosideA is the main component of rhubarb and Senna. Intraperitoneal administration of oral Senna A at A dose of 100% laxative rate to mice was nearly ineffective. The strength of its laxative effect, with oral, intraperitoneal administration, intravenous injection weakened. Intestinal delivery experiment, oral Senna
Key words:
Senna Rhein mouse intracavitary administration purgative activity oral strength of action major components purgative effect agent
year:
1980
Last Update：2023-08-16 22:09:50
517-43-1 - Study on the content of total sennoside in Xuelian tea and its Influencing factors
from titanium academic
Author:
Gulina Shaber , Ni hui , Jia Xinyue , Jia Xiaoguang , Qing de gang
Abstract:
Saussurea involucrata tea is composed of Saussurea involucrata, safflower and senna leaf. Senna is a dried lobule of the leguminous plant Cassia angustifolia Vahl or caseufofolia Senna cassiana Delile. Pharmacopoeia records its efficacy for purging heat line stagnation, laxative, diuresis. The main ingredients are Sennoside A,B,C and D, all belong to the two anthracene ketone compounds. The storage and determination of senna leaves are affected by light, temperature and time. In order to ensure the efficacy of the product and control the quality of the product, in this paper, the determination method and influencing factors of senna leaf in Saussurea involucrata Runtong tea were discussed by UV spectrophotometry, which provided a reference for the quality control of similar products.Key words:
Xuelian tea Total sennosides influencing factors Quality Control UV spectrophotometry Content determination
DOI:
10.3969/j.issn.1009-3931.2004.04.008
year:
2004
Last Update：2023-08-16 22:09:50
517-43-1 - Determination of sennoside and its metabolite sennoside by HPLC
Author:
Sun Yan , Li Xuemao , Star torch
Abstract:
sennosides A and B and their metabolites sennosides A and B were separated and determined by high performance liquid chromatography. The chromatographic conditions were as follows: column Spherisorb C18 stainless steel column (250 × 4.6mm I. d., 10 μm), column temperature 40 ℃; Detection wavelength 360 nm; Mobile phase A was 1.25% (volume fraction) acetic acid aqueous solution, mobile phase B was methanol, linear gradient program was 100
.Last Update：2023-08-16 22:09:50
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