5248-39-5
4-Methoxy-N,6-dimethyl-1,3,5-triazin-2-amine
CAS: 5248-39-5
Molecular Formula: C6H10N4O
5248-39-5 - Names and Identifiers
5248-39-5 - Physico-chemical Properties
| Molecular Formula | C6H10N4O |
| Molar Mass | 154.17 |
| Density | 1.196±0.06 g/cm3(Predicted) |
| Melting Point | 162-166°C(lit.) |
| Boling Point | 304.9±25.0 °C(Predicted) |
| Flash Point | 138.2°C |
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| Vapor Presure | 0.000847mmHg at 25°C |
| Appearance | Yellow crystal |
| Color | Pale Beige |
| pKa | 3.80±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.559 |
| MDL | MFCD00585858 |
| Physical and Chemical Properties | This product is a white solid, m.p.155 ~ 157 ℃, soluble in acetonitrile, xylene and other solvents, insoluble in water. |
| Use | As a pesticide herbicide Intermediate |
5248-39-5 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R48 - Danger of serious damage to health by prolonged exposure R48/22 - Harmful danger of serious damage to health by prolonged exposure if swallowed. R37 - Irritating to the respiratory system R21/22 - Harmful in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S22 - Do not breathe dust. S2 - Keep out of the reach of children. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| RTECS | XY2905180 |
5248-39-5 - Upstream Downstream Industry
| Raw Materials | Acetic anhydride Methyl alcohol Methyl alcohol Dicyandiamide Hydrochloric acid Hydrochloric acid |
5248-39-5 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Use | 2-methylamino-4-methoxy-6-methyl-triazine is an intermediate of the sulfonylurea herbicide bensulfuron. Used as pesticide and herbicide intermediate pesticide intermediate. |
| production method | the preparation method is as follows. (1) Add 2-amino -4-methoxy -6-methyltriazine and concentrated hydrochloric acid into the reaction kettle, stir and heat to 40 ℃, drop the mixed solution of formaldehyde and formic acid, finish the addition, keep the temperature at 45~55 ℃ for 3 h, raise the temperature and reflux for 4 h, then cool to 80 ℃, then add concentrated hydrochloric acid, then heat until the internal temperature of the reaction solution is 120 ℃, then drop to room temperature, add sodium hydroxide solution, adjust pH = 8, filter, crystallize, wash with water, and dry to obtain the finished product. (2) Use methyl chloride and magnesium strips to form the Grignard reagent of chloromethyl magnesium, drop it into the tetrahydrofuran solution of cyanuric chloride at room temperature, then remove tetrahydrofuran, add chloroform to obtain a methyl dichlorotriazine chloroform solution, add methylamine aqueous solution dropwise to the above solution, and then add sodium carbonate aqueous solution dropwise, react for 2h, stratify, the organic layer was desoluted to obtain 2-methylamino-4-methyl-6-chlorotriazine. Add methanol to the above-mentioned monochlorotriazine, add sodium methoxide methanol solution dropwise, reflux steam out methanol, add water to obtain precipitation, filter, and dry to obtain the finished product. Methyl bromide can also be used instead of methyl chloride for the reaction. (3) Using 2-amino -4-methoxy-6-methyltriazine as raw material, sodium methoxide is added to methanol, and then dimethyl carbonate and N,N-dimethylacetamide are added to react first to generate the corresponding methoxyformamide, then dimethyl sulfate is added dropwise for aminomethylation, and finally the finished product is obtained by hydrolysis. In the above three methods, if 2-amino-6-methyl-4-methoxytriazine is used as the raw material, if the reaction is incomplete, the product contains the above impurities, and the reaction with sulfonamide will produce messulfuron-methyl, which is harmful to crops, and cyanuric chloride is used as the raw material. Although the process is more complicated, the product purity is high, which can ensure the quality of the subsequent product tribenuron-methyl. At present, all production plants use the cyanuric chloride method to produce this intermediate. |
Last Update：2024-04-10 22:29:15
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Product Name: 4-Methoxy-N,6-dimethyl-1,3,5-triazin-2-amine Request for quotation
CAS: 5248-39-5
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CAS: 5248-39-5
Tel: 17505222756
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Product Name: 2-Methoxy-4-methyl-6-(methylamino)-1,3,5-triazine Visit Supplier Webpage Request for quotation
CAS: 5248-39-5
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CAS: 5248-39-5
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Raw Materials for 5248-39-5