53007-06-0 - Names and Identifiers
Name | N-Formylcytisine
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Synonyms | O-formylcytisine N-Formylcytisine PCYQRXYBKKZUSR-VHSXEESVSA-N [1R,(-)]-3-Formyl-1,2,3,4,5,6-hexahydro-1α,5α-methano-8H-pyrido[1,2-a][1,5]diazocine-8-one 1,5-Methano-2H-pyrido[1,2-a][1,5]diazocine-3(4H)-carboxaldehyde, 1,5,6,8-tetrahydro-8-oxo-, (1R,5S)-
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CAS | 53007-06-0
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53007-06-0 - Physico-chemical Properties
Molecular Formula | C12H14N2O2
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Molar Mass | 218.25 |
Density | 1.31±0.1 g/cm3(Predicted) |
Melting Point | l70-2°C |
Boling Point | 512.8±49.0 °C(Predicted) |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
Appearance | Powder |
pKa | 0.00±0.20(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Bioactive N-Formylcytisine is an alkaloid extracted from the stem bark of Maackia amurensis. |
53007-06-0 - Upstream Downstream Industry
53007-06-0 - Introduction
N-Formylcytisine is a natural alkaloid, also known as N-Formylcytisine. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Chemical formula: C12H16N2O2
2. Molecular Weight: 220.27g/mol
3. Appearance: white crystalline powder
4. Melting Point: 147-148 ° C
5. Solubility: Soluble in ethanol and dichloromethane, slightly soluble in water
6. Chemical properties: N-Formylcytisine is a natural alkaloid, with nerve activity and muscle relaxation.
Use:
1. Medical use: The N-Formylcytisine is used to study the activity of inhibiting human sigmoid colon cancer cells and may have potential anti-tumor activity.
2. Tobacco alternatives: Because of their similar effects to nicotine, N-Formylcytisine is being studied as a potential option for tobacco withdrawal and substitution.
Method:
N-Formylcytisine can be prepared by N-formylation of genitine. The specific preparation method can be:
Genaquine is reacted with Formic Anhydride to generate N-Formylcytisine.
Safety Information:
1. N-Formylcytisine need to be stored under dark conditions to avoid decomposition caused by light.
2. In handling and use, should take appropriate personal protective measures, such as wearing gloves and respiratory protective equipment.
3. The compound has not been widely used, so there are limited safety data for long-term use and chronic exposure, and it should be used with caution.
4. A detailed risk assessment should be carried out before use and operated in accordance with the local regulations.
Last Update:2024-04-10 22:29:15