53491-80-8
1-Chloroisoquinoline-4-carbonitrile
CAS: 53491-80-8
Molecular Formula: C10H5ClN2
53491-80-8 - Names and Identifiers
| Name | 1-Chloroisoquinoline-4-carbonitrile |
| Synonyms | 1-Chloro-4-isoquinolinecarbonitrile 1-Chloroisoquinoline-4-carbonitrile 4-Isoquinolinecarbonitrile, 1-chloro- |
| CAS | 53491-80-8 |
53491-80-8 - Physico-chemical Properties
| Molecular Formula | C10H5ClN2 |
| Molar Mass | 188.61 |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Boling Point | 355.2±22.0 °C(Predicted) |
| pKa | -1.36±0.31(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD13193485 |
53491-80-8 - Introduction
It is an organic compound with the chemical formula C10H5ClN2. The following is a description of its nature, use, preparation and safety information.
Nature:
is a yellow solid with a special aroma. It is insoluble in water at normal temperature, but soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
Use:
It has a certain application in the field of chemical synthesis. It can be used as an intermediate in the synthesis of other organic compounds, such as some drugs in the pharmaceutical industry.
Preparation Method:
A common method of synthesis of the compound is by reduction and cyanation of nitroisoquinoline. Specific steps include reacting nitroisoquinoline with a reducing agent (such as ammonium phosphite or sodium bisulfite) to obtain 1-amino-4-chloroisoquinoline, which is then subjected to cyanation.
Safety Information:
It is an organic compound and needs to be safe during use or storage. It may cause irritation and damage to the eyes, skin and respiratory tract, so personal protective equipment should be worn during operation. In addition, it also has certain potential hazards to the environment and should be avoided.
Nature:
is a yellow solid with a special aroma. It is insoluble in water at normal temperature, but soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
Use:
It has a certain application in the field of chemical synthesis. It can be used as an intermediate in the synthesis of other organic compounds, such as some drugs in the pharmaceutical industry.
Preparation Method:
A common method of synthesis of the compound is by reduction and cyanation of nitroisoquinoline. Specific steps include reacting nitroisoquinoline with a reducing agent (such as ammonium phosphite or sodium bisulfite) to obtain 1-amino-4-chloroisoquinoline, which is then subjected to cyanation.
Safety Information:
It is an organic compound and needs to be safe during use or storage. It may cause irritation and damage to the eyes, skin and respiratory tract, so personal protective equipment should be worn during operation. In addition, it also has certain potential hazards to the environment and should be avoided.
Last Update：2024-04-09 20:52:54
