5378-35-8
3-[1,3,4]Oxadiazol-2-yl-phenylamine
CAS: 5378-35-8
Molecular Formula: C8H7N3O
5378-35-8 - Names and Identifiers
| Name | 3-[1,3,4]Oxadiazol-2-yl-phenylamine |
| Synonyms | 3-(1,3,4-OXADIAZOL-2-YL)ANILINE 3-[1,3,4]Oxadiazol-2-yl-phenylamine Benzenamine, 3-(1,3,4-oxadiazol-2-yl)- |
| CAS | 5378-35-8 |
5378-35-8 - Physico-chemical Properties
| Molecular Formula | C8H7N3O |
| Molar Mass | 161.16 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD00099501 |
5378-35-8 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
5378-35-8 - Introduction
3-[1,3,4]Oxadiazol-2-yl-phenylamine is an organic compound with the formula C8H7N3O, which has the appearance of a white crystalline solid.
Nature:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is a compound with high melting point and low solubility. Its solubility in solvents is low, but it can be dissolved in some organic solvents such as chloroform, methanol and dimethylformamide. This compound is not stable in the presence of sunlight and oxygen.
Use:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is an important intermediate in organic synthesis. It can be used to synthesize various organic compounds such as fluorescent dyes, pesticides and drugs.
Preparation Method:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is commonly prepared by reacting aniline with 1,3, 4-oxadiazole-2-iodomethane. First, under alkaline conditions, aniline reacts with 1,3, 4-oxadiazole-2-iodomethane to generate intermediates, and then undergoes a reduction reaction to obtain the target product.
Safety Information:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is a toxic compound, which is harmful to human body and environment. In case of contact with skin, eyes or inhalation of dust, rinse immediately with plenty of water and seek medical help. During operation and storage, avoid contact with oxygen, sunlight and fire sources to prevent fire or explosion. Appropriate personal protective equipment such as gloves, goggles and protective clothing must be worn when using the compound. In addition, when handling 3-[1,3,4]Oxadiazol-2-yl-phenylamine, the regulations for safe handling of chemicals should be observed.
Nature:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is a compound with high melting point and low solubility. Its solubility in solvents is low, but it can be dissolved in some organic solvents such as chloroform, methanol and dimethylformamide. This compound is not stable in the presence of sunlight and oxygen.
Use:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is an important intermediate in organic synthesis. It can be used to synthesize various organic compounds such as fluorescent dyes, pesticides and drugs.
Preparation Method:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is commonly prepared by reacting aniline with 1,3, 4-oxadiazole-2-iodomethane. First, under alkaline conditions, aniline reacts with 1,3, 4-oxadiazole-2-iodomethane to generate intermediates, and then undergoes a reduction reaction to obtain the target product.
Safety Information:
3-[1,3,4]Oxadiazol-2-yl-phenylamine is a toxic compound, which is harmful to human body and environment. In case of contact with skin, eyes or inhalation of dust, rinse immediately with plenty of water and seek medical help. During operation and storage, avoid contact with oxygen, sunlight and fire sources to prevent fire or explosion. Appropriate personal protective equipment such as gloves, goggles and protective clothing must be worn when using the compound. In addition, when handling 3-[1,3,4]Oxadiazol-2-yl-phenylamine, the regulations for safe handling of chemicals should be observed.
Last Update：2024-04-09 21:01:54
